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van CCT (UK)

van CCT (UK)

Train alcoholism away

- candidate number3115
- NTR NumberNTR1249
- ISRCTNISRCTN wordt niet meer aangevraagd
- Date ISRCTN created
- date ISRCTN requested
- Date Registered NTR13-mrt-2008
- Secondary IDs07-3-099 MEC
- Public TitleTrain alcoholism away
- Scientific TitleRetraining automatic action tendencies and attentional bias in individuals with alcohol dependency problems
- ACRONYMAlcoholtraining
- hypothesisMain hypothesis of this study is that re-training of an attentional bias for alcohol, decreases the attentional bias for alcoholic stimuli, and that a re-training the automatic approach bias for alcoholic stimuli decreases this cognitive bias.
Further, this study will investigate whether the effects of each training are specific for each bias, or if the training of attentional bias will also effect the approach bias and vice versa. Finally, we will also study the effects of both varieties of training on several clinically relevant variables, such as relapse, craving and motivation to change drinking behaviour.
- Healt Condition(s) or Problem(s) studiedAlcoholism
- Inclusion criteria1. Adult (18-65) patients treated for alcohol dependence (DSM IV)
- Exclusion criteria1. Low intellectual ability
2. Psychotic problems
3. Depression or other Axis 1 disorder which needs urgent treatment.
- mec approval receivedyes
- multicenter trialyes
- randomisedyes
- masking/blindingSingle
- controlActive
- groupFactorial
- Type2 or more arms, randomized
- Studytypeintervention
- planned startdate 1-mrt-2008
- planned closingdate1-jun-2009
- Target number of participants100
- InterventionsDifferent varieties of "re-training" of attentional bias for alcohol or of automatic approach tendencies for alcohol
- Primary outcomeAttentional bias for alcohol
Approach bias for alcohol
Subjective craving
Treatment outcome (relapse)
- Secondary outcomeSelf-efficacy
- TimepointsDirect post-training; + 1 month; + 3 months
- Trial web siteN/A
- statusplanned
- Sponsor/Initiator University Maastricht (UM)
- Funding
(Source(s) of Monetary or Material Support)
- PublicationsWiers, R. W., Cox, W. M., Field, M. Fadardi, J. S., Palfai, T. P., Schoenmakers, T. & Stacy, A. W. (2006). The search for new ways to change implicit alcohol-related cognitions in heavy drinkers. Alcoholism, Clinical and Experimental Research, 30, 320-331.
- Brief summaryParticipants are allocated to one of the training varieties, either focussing on an attentional bias or on an approach bias or to a placebo-training. Prior research has shown that these biases are related to addictive behaviors, including alcohol dependence.
The different forms of training consist of computer tasks in which alcohol related en neutral stimuli are presented, to which participants have to respond. In the attentional training the participant learns to steer their attention away from the alcoholic stimuli, and during the automatic approach training or action tendency training (ATT), participants learn to push alcohol away (training an avoidance response instead of an approach response). In one of the varieties of the action tendency training, the participant is instructed to respond to the relevant features of the presented stimuli (push alcohol pictures away), in the other varieties and in the placebo-control condition they are instructed to respond to an irrelevant feature of the presented pictures (for example; pull all the pictures presented in landscape format toward you, and push all pictures presented in portrait format away). The automatic tendency from the participants to approach alcohol will be influenced during these trainings sessions by presenting (almost) all alcohol related pictures in the format which is pushed away, and (almost) all soda pictures in the format which is pulled. In the control condition the push/pull ratio for alcohol and softdrink pictures is set at 50%.
- Main changes (audit trail)
- RECORD13-mrt-2008 - 3-apr-2008

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