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Patellar denervation in total knee arthroplasty.


- candidate number3318
- NTR NumberNTR1326
- ISRCTNISRCTN wordt niet meer aangevraagd
- Date ISRCTN created
- date ISRCTN requested
- Date Registered NTR25-mei-2008
- Secondary IDsNL21569.075.08 
- Public TitlePatellar denervation in total knee arthroplasty.
- Scientific TitleCircumpatellar electrocautery denervation in total knee arthroplasty without patellar resurfacing: a prospective randomized study with 1-year follow-up.
- ACRONYMMOPPER
- hypothesisThe null hypothesis is that there is no difference in terms of pain and clinical outcome between total knee arthroplasty with and that without circumpatellar electrocautery denervation.
- Healt Condition(s) or Problem(s) studiedElectrocautery, Arthroplasty , Total knee arthroplasty, Patella, Denervation
- Inclusion criteriaAll patients who will be treated with a total knee arthroplasty without patellar resurfacing in the Deventer hospital.
- Exclusion criteria1. Isolated patellofemoral osteoarthritis.
2. Contralateral patellar resurfacing (primary or as revision).
3. Insufficient Dutch language skills.
4. Total hip replacement or contralateral total knee replacement within the study period or less than one year before entering the study
5. Inflammatory arthritis.
6. History of patellar fracture.
7. Prior patellectomy.
8. Patellofemoral instability.
9. Prior unicondylar knee replacement.
10. Previous high tibial or distal femoral osteotomy.
11. Any prior operation involving the extensor mechanism.
12. A severe medical disability that limits the ability to walk.
13. Disabling disease involving other joints of the lower extremities.
- mec approval receivedyes
- multicenter trialno
- randomisedyes
- masking/blindingDouble
- controlActive
- groupParallel
- Type2 or more arms, randomized
- Studytypeintervention
- planned startdate 1-apr-2008
- planned closingdate31-dec-2012
- Target number of participants200
- InterventionsCircumpatellar electrocautery denervation in total knee arthroplasty without patellar resurfacing.
- Primary outcomePrevalence of anterior knee pain using the Clinical Anterior Knee Pain Rating.
- Secondary outcomePain on a Visual Analogue Scale (VAS). WOMAC 3.1 Osteoarthritis Index. Knee Society Score.
- TimepointsPreoperative, 12 months, 2 years and 4 years after total knee arthroplasty.
- Trial web siteN/A
- statusinclusion stopped: follow-up
- CONTACT FOR PUBLIC QUERIESMD Hans-Peter W. Jonbergen, van
- CONTACT for SCIENTIFIC QUERIESMD Hans-Peter W. Jonbergen, van
- Sponsor/Initiator Deventer Ziekenhuis, Department of Orthopaedic Surgery
- Funding
(Source(s) of Monetary or Material Support)
Deventer Ziekenhuis, Department of Orthopaedic Surgery
- PublicationsN/A
- Brief summaryAnterior knee pain occurs in up to 31% of patients after total knee arthroplasty without patellar resurfacing, and in approximately up to 16% of patients with patellar resurfacing. The cause of patellofemoral pain after total knee arthroplasty is unknown but may at least be partly related to postoperative malalignment and anatomic variations resulting in high patellofemoral contact forces. Immunohistochemical studies on innervation of the anterior knee have found hyperinnervation in the peripatellar soft tissues. In theory, circumpatellar denervation using electrocautery could result in a lower prevalence of anterior knee pain. To date, no relevant clinical studies addressed the results of circumpatellar electrocautery denervation in total knee arthroplasty without patellar resurfacing. Primary objective was therefore to determine the effect of circumpatellar electrocautery denervation in total knee arthroplasty without patellar resurfacing, particularly with regard to anterior knee pain.
- Main changes (audit trail)
- RECORD25-mei-2008 - 11-jan-2011


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