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Control of heat storage in a cool and warm environment in young and elderly males.


- candidate number6453
- NTR NumberNTR2007
- ISRCTNISRCTN wordt niet meer aangevraagd.
- Date ISRCTN created
- date ISRCTN requested
- Date Registered NTR11-sep-2009
- Secondary IDs09-3-049 MEC Maastricht University
- Public TitleControl of heat storage in a cool and warm environment in young and elderly males.
- Scientific TitleControl of heat storage in a cool and warm environment in young and elderly males.
- ACRONYMHEATAGE
- hypothesisTest the hypothesis that a divisional calculation of heat loss, and incorporation of skin temperature of the extremities during mild cold exposure will indicate an age effect on heat loss between young and elderly. An additional purpose is to test whether age effects on hysteresis are observable between cooling and warming subjects.
- Healt Condition(s) or Problem(s) studiedTemperature, Age, Hysteresis, Thermoregulation, Skin blood flow
- Inclusion criteria1. Caucasian healthy male;
2. Age between 18 to 28 years or age between 68 to 78 years;
3. 20 kg/m2 < BMI < 25 kg/m2;
4. 15% < Fat percentage < 20%;
5. 1.8 m2 < Dubois skin area < 2.0 m2;
6. 80mmHg < Mean arterial pressure < 90mmHg (rest, supine position).
- Exclusion criteria1. Female;
2. History of cardiovascular disease;
3. Carrier of electrically-sensitive implanted devices;
4. Deviant core temperature at day of experiment;
5. General feeling of illness at day of experiment.
- mec approval receivedno
- multicenter trialno
- randomisedyes
- masking/blindingNone
- controlNot applicable
- groupParallel
- Type2 or more arms, randomized
- Studytypeobservational
- planned startdate 11-jan-2009
- planned closingdate11-jan-2010
- Target number of participants24
- InterventionsSubjects subjected to a mild cold (airtemperature 20C) and mild heat exposure (airtemperature 35C).
- Primary outcome1. Heat loss (W);
2. Heat content (J/m^3).
- Secondary outcomeN/A
- TimepointsN/A
- Trial web siteN/A
- statusopen: patient inclusion
- CONTACT FOR PUBLIC QUERIES Boris Kingma
- CONTACT for SCIENTIFIC QUERIES Boris Kingma
- Sponsor/Initiator University Maastricht (UM)
- Funding
(Source(s) of Monetary or Material Support)
SenterNovem
- PublicationsN/A
- Brief summaryIn general elderly are predisposed to risk of both hypothermia and hyperthermia, even at mild cold or heat exposure. Studies aimed at age related changes in mechanisms of thermoregulation to explain the increased risk of elderly failed to observe differences in heat loss between young and elderly. This might be caused by a lumped approach of calculation of heat loss through mean skin temperature without incorporation of temperatures of the extremities.
- Main changes (audit trail)
- RECORD11-sep-2009 - 12-okt-2009


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