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van CCT (UK)

van CCT (UK)

Vivid memories.

- candidate number8106
- NTR NumberNTR2348
- ISRCTNISRCTN wordt niet meer aangevraagd.
- Date ISRCTN created
- date ISRCTN requested
- Date Registered NTR1-jun-2010
- Secondary IDsNL32189.068.10 CCMO
- Public TitleVivid memories.
- Scientific TitlePrevention of vivid memories.
- hypothesisSoldiers deployed to Afghanistan who play the computergame "Tetris” within 24 hours after an aversive event show larger reductions in frequency of event-related intrusive memories at 1 week after the event than soldiers who do not play “Tetris”.
- Healt Condition(s) or Problem(s) studiedPost-Traumatic Stress Disorder (PTSD), Intrusive memories
- Inclusion criteria1. Exposure to an event according to the stressor A1 criterion of the DSM IV; (American Psychiatric Association, 1994);
2. The event happened no longer than 24 hours earlier.
- Exclusion criteriaRespondents are excluded if they:
1. Are not fully conscious at the time of the intervention;
2. Are severely injured (i.e., physically unable of undergoing the intervention);
3. Are suicidal;
4. Meet the criteria for any of the following DSM-IV diagnoses: psychotic disorders, bipolar disorder, depression with psychotic features, or PTSD.
- mec approval receivedyes
- multicenter trialyes
- randomisedyes
- masking/blindingSingle
- controlActive
- groupParallel
- Type2 or more arms, randomized
- Studytypeintervention
- planned startdate 1-jul-2010
- planned closingdate31-dec-2011
- Target number of participants102
- InterventionsParticipants will be randomly allocated to one of two conditions:
1. Tetris (n=51);
2. Assessments Only (n=51).
The Tetris group will be asked to repeatedly bring the event to mind, while playing Tetris on a computer for 30 minutes. The Assessments Only group will be administered the same pre measures used in the Tetris group, and are asked to return after 30 min. to complete the post assessment. Both groups will be offered care as usual by the Dutch Defense Military Mental Health.
- Primary outcomeFrequency of intrusions measured with a structured clinical interview at 1 week after the aversive event.
- Secondary outcome1. Vividness and emotionality of intrusions immediately post-intervention, 1 week after the event, and 6 weeks after deployment;
2. PTSD symptom severity at 1 week after the aversive event and 6 weeks after deployment.
- TimepointsAssessments will be scheduled before the intervention, immediately post-intervention, 1 week after the intervention and 6 weeks after deployment.
- Trial web siteN/A
- statusplanned
- Sponsor/Initiator Utrecht University (UU)
- Funding
(Source(s) of Monetary or Material Support)
NWO (VIDI grant)
- PublicationsEngelhard, I. M., van den Hout, M. A., Weerts, J., Arntz, A., Hox, J. J., & McNally, R. J. (2007). Deployment-related stress and trauma in Dutch soldiers returning from Iraq. Prospective study. Br.J.Psychiatry, 191, 140-145.
Engelhard, I. M. & van den Hout, M. A. (2007). Preexisting neuroticism, subjective stressor severity, and posttraumatic stress in soldiers deployed to Iraq. Can.J.Psychiatry, 52, 505-509.
Engelhard, I. M., van den Hout, M. A., Janssen, W. C., & van der, B. J. (2010). Eye movements reduce vividness and emotionality of "flashforwards". Behav.Res.Ther.
Holmes, E. A., James, E. L., Coode-Bate, T., & Deeprose, C. (2009). Can playing the computer game "Tetris" reduce the build-up of flashbacks for trauma? A proposal from cognitive science. PLoS.One., 4, e4153.
Sijbrandij, M., Olff, M., Reitsma, J. B., Carlier, I. V., De Vries, M. H., & Gersons, B. P. (2007). Treatment of acute posttraumatic stress disorder with brief cognitive behavioral therapy: a randomized controlled trial. Am.J.Psychiatry, 164, 82-90.
Sijbrandij, M., Olff, M., Reitsma, J. B., Carlier, I. V., & Gersons, B. P. (2006a). Emotional or educational debriefing after psychological trauma. Randomised controlled trial. Br.J.Psychiatry, 189, 150-155.
- Brief summaryN/A
- Main changes (audit trail)
- RECORD1-jun-2010 - 10-jun-2010

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