|- candidate number||8106|
|- NTR Number||NTR2348|
|- ISRCTN||ISRCTN wordt niet meer aangevraagd.|
|- Date ISRCTN created|
|- date ISRCTN requested|
|- Date Registered NTR||1-jun-2010|
|- Secondary IDs||NL32189.068.10 CCMO|
|- Public Title||Vivid memories.|
|- Scientific Title||Prevention of vivid memories.|
|- hypothesis||Soldiers deployed to Afghanistan who play the computergame "Tetris” within 24 hours after an aversive event show larger reductions in frequency of event-related intrusive memories at 1 week after the event than soldiers who do not play “Tetris”. |
|- Healt Condition(s) or Problem(s) studied||Post-Traumatic Stress Disorder (PTSD), Intrusive memories|
|- Inclusion criteria||1. Exposure to an event according to the stressor A1 criterion of the DSM IV; (American Psychiatric Association, 1994);|
2. The event happened no longer than 24 hours earlier.
|- Exclusion criteria||Respondents are excluded if they:|
1. Are not fully conscious at the time of the intervention;
2. Are severely injured (i.e., physically unable of undergoing the intervention);
3. Are suicidal;
4. Meet the criteria for any of the following DSM-IV diagnoses: psychotic disorders, bipolar disorder, depression with psychotic features, or PTSD.
|- mec approval received||yes|
|- multicenter trial||yes|
|- Type||2 or more arms, randomized|
|- planned startdate ||1-jul-2010|
|- planned closingdate||31-dec-2011|
|- Target number of participants||102|
|- Interventions||Participants will be randomly allocated to one of two conditions:|
1. Tetris (n=51);
2. Assessments Only (n=51).
The Tetris group will be asked to repeatedly bring the event to mind, while playing Tetris on a computer for 30 minutes. The Assessments Only group will be administered the same pre measures used in the Tetris group, and are asked to return after 30 min. to complete the post assessment. Both groups will be offered care as usual by the Dutch Defense Military Mental Health.
|- Primary outcome||Frequency of intrusions measured with a structured clinical interview at 1 week after the aversive event.|
|- Secondary outcome||1. Vividness and emotionality of intrusions immediately post-intervention, 1 week after the event, and 6 weeks after deployment;|
2. PTSD symptom severity at 1 week after the aversive event and 6 weeks after deployment.
|- Timepoints||Assessments will be scheduled before the intervention, immediately post-intervention, 1 week after the intervention and 6 weeks after deployment. |
|- Trial web site||N/A|
|- CONTACT FOR PUBLIC QUERIES|| M. Sijbrandij|
|- CONTACT for SCIENTIFIC QUERIES|| M. Sijbrandij|
|- Sponsor/Initiator ||Utrecht University (UU)|
(Source(s) of Monetary or Material Support)
|NWO (VIDI grant)|
|- Publications||Engelhard, I. M., van den Hout, M. A., Weerts, J., Arntz, A., Hox, J. J., & McNally, R. J. (2007). Deployment-related stress and trauma in Dutch soldiers returning from Iraq. Prospective study. Br.J.Psychiatry, 191, 140-145.
Engelhard, I. M. & van den Hout, M. A. (2007). Preexisting neuroticism, subjective stressor severity, and posttraumatic stress in soldiers deployed to Iraq. Can.J.Psychiatry, 52, 505-509.
Engelhard, I. M., van den Hout, M. A., Janssen, W. C., & van der, B. J. (2010). Eye movements reduce vividness and emotionality of "flashforwards". Behav.Res.Ther.
Holmes, E. A., James, E. L., Coode-Bate, T., & Deeprose, C. (2009). Can playing the computer game "Tetris" reduce the build-up of flashbacks for trauma? A proposal from cognitive science. PLoS.One., 4, e4153.
Sijbrandij, M., Olff, M., Reitsma, J. B., Carlier, I. V., De Vries, M. H., & Gersons, B. P. (2007). Treatment of acute posttraumatic stress disorder with brief cognitive behavioral therapy: a randomized controlled trial. Am.J.Psychiatry, 164, 82-90.
Sijbrandij, M., Olff, M., Reitsma, J. B., Carlier, I. V., & Gersons, B. P. (2006a). Emotional or educational debriefing after psychological trauma. Randomised controlled trial. Br.J.Psychiatry, 189, 150-155.
|- Brief summary||N/A|
|- Main changes (audit trail)|
|- RECORD||1-jun-2010 - 10-jun-2010|
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