|- candidate number||9199|
|- NTR Number||NTR2793|
|- ISRCTN||ISRCTN wordt niet meer aangevraagd.|
|- Date ISRCTN created|
|- date ISRCTN requested|
|- Date Registered NTR||4-mrt-2011|
|- Secondary IDs||NL34553.081.11 / 10/30; ABR / Protocol nr. WUR|
|- Public Title||"Mum can I have some more vegetables today?"|
GRIP-Studie (GRoente Inname Peuters).
|- Scientific Title||Effectiveness of flavour nutrient learning as a mechanism to increase children's preference for vegetables.|
|- hypothesis||To investigate if flavour nutrient learning is an effective mechanism to increase children's vegetable intake. Is there an effect?|
|- Healt Condition(s) or Problem(s) studied||Vegetables, Toddlers, Intake, Preferences|
|- Inclusion criteria||1. Healty toddlers;|
2. 1.9 - 4 years old;
3. With persmission from their parents to participate.
|- Exclusion criteria||1. Parents will not sign the informed consent;|
2. Children wtih a food allergy for one of the substances used in the study such as maltodextrin, sun flower oil, rice flour, spinach or endive.
|- mec approval received||yes|
|- multicenter trial||no|
|- control||Not applicable|
|- Type||2 or more arms, randomized|
|- planned startdate ||1-mrt-2011|
|- planned closingdate||31-okt-2011|
|- Target number of participants||24|
|- Interventions||Intervention with nutrition (vegetables) based on therapeutical effect. Participants will learn an increased preference for vegetables.|
In 7 conditioning trials (14 days), children repeatedly consume ad random a fixed amount (125 gram) of two different vegetable products. The vegetable products differ in taste and energy content.
|- Primary outcome||Preference will be a main endpoint of the study. Preference will be measured in two ways:|
1. Two pair preference test of two vegetable products;
2. Two-flavour consumption test: The children will be invited to eat as much as they want from the two target vegetable products on different days, both as LE versions (ad libitum consumption). Consumption will be used as an indicator of preference.
|- Secondary outcome||Consumption data during the conditioning trials to measure if at least 70% of each of the product is consumed (Johnson, 1991).
After each conditioning trial the consumption of the lunch will be registered to provide evidence regarding children’s responsiveness to the caloric density manipulation.
|- Timepoints||The GRIP-study is a conditioning study at a daycare of 9 weeks with 2 durability tests to investigate the sustainability of the mechanism, one after 2 months and one after 6 months if there is an increase on intake. In 7 conditioning trials (14 days), children repeatedly consume ad random a fixed amount (125 gram) of two different vegetable products. The vegetable products differ in taste and energy content. |
|- Trial web site||voedingsonderzoek.wur.nl/grip|
|- status||open: patient inclusion|
|- CONTACT FOR PUBLIC QUERIES||Ir. Victoire Wild, de|
|- CONTACT for SCIENTIFIC QUERIES||Prof. K. Graaf, de|
|- Sponsor/Initiator ||Wageningen University (WUR)|
(Source(s) of Monetary or Material Support)
|- Brief summary||Rationale:|
Children’s consumption of vegetables is below recommendations. Since preference is the most important predictor of children’s intake and most children dislike vegetables, new strategies are needed to increase their preferences for vegetables. Flavour-nutrient learning is one of the effective mechanisms to change preferences.
To understand more of the learning principles of vegetable consumption in young children (2-4 years). The aim of this study is to investigate the effect of flavour nutrient learning on vegetable preference and intake.
|- Main changes (audit trail)|
|- RECORD||4-mrt-2011 - 13-mrt-2011|