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van CCT (UK)


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van CCT (UK)


MRI and clinical exam for staging cervical carcinoma: Systematic review and meta-analysis.


- candidate number9405
- NTR NumberNTR2896
- ISRCTNISRCTN wordt niet meer aangevraagd.
- Date ISRCTN created
- date ISRCTN requested
- Date Registered NTR2-mei-2011
- Secondary IDs 
- Public TitleMRI and clinical exam for staging cervical carcinoma: Systematic review and meta-analysis.
- Scientific TitleMRI and clinical exam for staging cervical carcinoma: Systematic review and meta-analysis.
- ACRONYM
- hypothesisIs MRI needed in the staging of cervical carcinoma?
- Healt Condition(s) or Problem(s) studiedCervix cancer
- Inclusion criteriaWomen with primary cervical carcinoma with intention of operative treatment.
- Exclusion criteria1. The article was not written in English;
2. The article is not about primary cervical carcinoma;
3. The article is not about adenocarcinoma or squamous or adenosquamous carcinoma;
4. The article has no diagnostic purpose;
5. The patients included in the study are already treated for cervical carcinoma;
6. The study has less than 10 patients included;
7. Patients include pregnant women;
8. The study is not using MRI or clinical examination as diagnostic tool;
9. The inability to obtain original numbers of true positives, false positives, true-negative and false-negatives;
10. There was a possible overlap of study samples;
11. The article was a review article or an editorial.
- mec approval receivedno
- multicenter trialno
- randomisedno
- groupParallel
- TypeSingle arm
- Studytypeobservational
- planned startdate 20-mei-2011
- planned closingdate20-nov-2011
- Target number of participants0
- InterventionsN/A
- Primary outcome1. Senstivity;
2. Specificity;
3. Pos pred value and neg pred value of MRI and clinical exam.
- Secondary outcomePublication bias.
- TimepointsN/A
- Trial web siteN/A
- statusopen: patient inclusion
- CONTACT FOR PUBLIC QUERIES Maarten Thomeer
- CONTACT for SCIENTIFIC QUERIES Maarten Thomeer
- Sponsor/Initiator Erasmus Medical Center
- Funding
(Source(s) of Monetary or Material Support)
Erasmus Medical Center
- PublicationsN/A
- Brief summaryTo review the literature on the diagnostic performance of magnetic resonance imaging and clinical investigation in detecting parametrial invasion, operability and tumor length with surgico-pathological results as reference standard.
- Main changes (audit trail)
- RECORD2-mei-2011 - 24-mei-2011


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