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Online prevention of anxiety and depression in adolescents.


- candidate number14715
- NTR NumberNTR3950
- ISRCTNISRCTN wordt niet meer aangevraagd.
- Date ISRCTN created
- date ISRCTN requested
- Date Registered NTR11-apr-2013
- Secondary IDs200210010 ZonMw
- Public TitleOnline prevention of anxiety and depression in adolescents.
- Scientific Title"Always look on the bright side of life": Increasing emotional resilience in adolescents by training cognitive processes to prevent anxiety and depression.
- ACRONYM
- hypothesisAnxiety and depression are highly prevalent in adolescents. Therefore, early and low threshold prevention is of great importance.
The aim of the current study is to test whether online training of a positive information processing style and cognitive control is successful in increasing resilience, reducing internalizing symptoms and preventing clinical disorders (anxiety/depression).
- Healt Condition(s) or Problem(s) studiedAnxiety, Depression, Working Memory, Cognitive control
- Inclusion criteria1. Scolars in 1st to 6th grade of high school (12-18 years);
2. VMBO, HAVO or VWO;
3. Parental consent.
- Exclusion criteriaEduction level below regular VMBO/special education.
- mec approval receivedyes
- multicenter trialno
- randomisedyes
- masking/blindingDouble
- controlPlacebo
- groupParallel
- Type2 or more arms, randomized
- Studytypeintervention
- planned startdate 7-jan-2012
- planned closingdate1-nov-2014
- Target number of participants600
- InterventionsAll conditions consist of 8 15-minute sessions of online computer training (twice a week).
1. Attentional bias training: dot-probe task;
2. Attention bias training: visual search task;
3. Interpretation bias training: scenario task;
4. Working memory training: block-tapping task;
5. Placebo-control training: inactive variants of training paradigms.
- Primary outcome1. Self-reported anxiety: Screen for Child Anxiety Related Emotional Disorders (SCARED, Birmaher et al., 1999);
2. Self-reported depression: Child Depression Inventory (CDI, Kovacs, 1992).
- Secondary outcome1. Rosenberg self-esteem scale (RSES, Rosenberg, 1965);
2. Self-report and parent report on internalizing and externalizing problems: Strengths and Difficulties Questionnaire - child and parent version (SDQ, Goodman, 1997);
3. Perseverative Thinking Questionnaire (PTQ, Ehring et al., 2011);
4. Prestatie Motivatie Test voor Kinderen (PMT-K, Hermans, 1983) (test anxiety);
5. Alcohol Use Disorders Identification Test (AUDIT, Saunders et al., 1993);
6. Attentional Control Scale (ACS; Derryberry & Reed, 2002);
7. Stressful life events;
8. Emotional response to social stress-task;
9. Emotional response to exam week;
10. Attentional bias, interpretation bias and working memory capacity will be assessed to see whether the training was successful in changing these processes.
- TimepointsAssessments at pre-training, post-training and 3, 6 and 12 months follow-up.
- Trial web siteN/A
- statusinclusion stopped: follow-up
- CONTACT FOR PUBLIC QUERIESMSc. E.L. Voogd, de
- CONTACT for SCIENTIFIC QUERIESDr. E. Salemink
- Sponsor/Initiator University of Amsterdam (UvA)
- Funding
(Source(s) of Monetary or Material Support)
ZON-MW, The Netherlands Organization for Health Research and Development
- PublicationsN/A
- Brief summaryIn this study, we test an online prevention program designed to increase emotional resilience and reduce and prevent anxiety and depression symptoms in adolescents. Participants (600) are recruited on high schools and randomly assigned to one of 5 training conditions (4 active, 1 placebo-control). Training focuses on attention and interpretation biases and cognitive control. Anxiety and depression symptoms and secondary outcome measures are assessed at pre- and post-training and 3, 6 and 12 months follow-up.
- Main changes (audit trail)
- RECORD11-apr-2013 - 17-okt-2013


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