search  
 


Home

Who are we?

Why
register?


Signup for
registration


Online registration

Log in to register
your trial


Search a trial

NRT en CCMO

Contact

NEDERLANDS





MetaRegister
van CCT (UK)


ISRCTN-Register
van CCT (UK)


ADASS study


- candidate number15652
- NTR NumberNTR4233
- ISRCTNISRCTN wordt niet meer aangevraagd.
- Date ISRCTN created
- date ISRCTN requested
- Date Registered NTR1-nov-2013
- Secondary IDsNL40743.072.012 CCMO registration number
- Public TitleADASS study
- Scientific TitleMINDFULNESS BASED STRESS REDUCTION (MBSR) AND COGNITIVE BEHAVIORAL THERAPY (CBT) FOR ADULTS WITH AUTISM SPECTRUM DISORDER (ASD)
- ACRONYM
- hypothesisDespite high rates of anxiety and depression among adults with ASD, treatment methods for these comorbid conditions have not been systematically studies or compared in this patient population. Recently, MBSR and CBT protocols were adapted for adults with ASD and could be excellent candidate therapies for reducing anxiety and depression. The study looks at the ability of both treatment methods to reduce anxiety and depression symptoms among adults with ASD, and to determine which therapy is best suited for which patient.
- Healt Condition(s) or Problem(s) studiedAutism
- Inclusion criteria1. adults with a clinical diagnosis of ADHD
2. normally intelligent
3. able to do homework assignments associated with treatment
4. score of > 8 on hospital anxiety and depression scale (HADS)
- Exclusion criteria- former treatment with mindfulness or cognitive behavioral therapy for adults with autism
- too sensitive for group treatment
- psychosis or under influence of alcohol or drugs
- mec approval receivedyes
- multicenter trialno
- randomisedyes
- masking/blindingNone
- controlNot applicable
- groupParallel
- Type2 or more arms, randomized
- Studytypeintervention
- planned startdate 1-okt-2013
- planned closingdate1-nov-2014
- Target number of participants180
- Interventions1. cognitive behavioral therapy addopted for adults with ASD (Schuurman, 2012) over a 13 week period
2. Mindfullness based stress reduction therapy for adults with ASD (Spek, 2012) over a 13 week period
3. Treatment as ususal
- Primary outcomereduction on anxiety scale and the depression scale of the hospital anxiety and depression scale (HADS)
- Secondary outcome1. changes on the social responsivity scale
2. changes in positive and negative affect on the global mood scalee
- Timepointsin each cycle:
Mo: at intake
M1: at start of the 13 week treatment period
M1a: after 4 weeks treatment
M1b: after 8 weeks treatment
M2: on completion of 13 week treatment period
M3: at 3 months follow up
- Trial web siteN/A
- statusopen: patient inclusion
- CONTACT FOR PUBLIC QUERIES B. Sizoo
- CONTACT for SCIENTIFIC QUERIES B. Sizoo
- Sponsor/Initiator Dimence
- Funding
(Source(s) of Monetary or Material Support)
Dimence
- PublicationsN/A
- Brief summaryA three-arm RCT among 180 adults with ASD (60 MBSR, 60 CBT, and 60 treatment as usual, (TAU)), conducted in an outpatient setting with measurements at the start and end of the 13 week treatment period, and at 3 months follow-up. Instruments include the hospital anxiety and depressions scale, rumination, irrational belief and mindfulness scales, and an autism symptom checklist
- Main changes (audit trail)
- RECORD1-nov-2013 - 19-nov-2013


  • Indien u gegevens wilt toevoegen of veranderen, kunt u een mail sturen naar nederlands@trialregister.nl