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van CCT (UK)

van CCT (UK)

Improving antibiotic use for patients with respiratory infection using an educational intervention

- candidate number15495
- NTR NumberNTR4239
- ISRCTNISRCTN wordt niet meer aangevraagd.
- Date ISRCTN created
- date ISRCTN requested
- Date Registered NTR3-okt-2013
- Secondary IDsZonMW 945-17-303 
- Public TitleImproving antibiotic use for patients with respiratory infection using an educational intervention
- Scientific TitleImplementation of a multiple intervention aimed at optimising prescription of antibiotics for respiratory tract infections, embedded within the new practice accreditation of the Dutch College of General Practitioners; a randomised controlled trial
- hypothesisEducation on guidelines, combined with quality targets within the accreditation procedure improves quality of antibiotic prescribing
- Healt Condition(s) or Problem(s) studiedAntibiotics, Respiratory tract infection, General practitioner, Nurse
- Inclusion criteriageneral practitioners willing to participate important to mention is that we include GPs of primary care practices and no individual patients. The number of participants therefore refer to the number of included practices.
- Exclusion criterianone
- mec approval receivedyes
- multicenter trialyes
- randomisedyes
- masking/blindingNone
- controlNot applicable
- groupParallel
- Type2 or more arms, randomized
- Studytypeintervention
- planned startdate 1-jan-2010
- planned closingdate1-jan-2014
- Target number of participants80
- InterventionsEducation at the primary care center (duration: 1 hour) will be provided to improve antibiotic prescribing for respiratory tract infections. In the control practices, education with respect to correct prescription of proton-pump inhibitors (PPI) will be given. Both groups serve as each others controles. The intervention is aimed at all general practitioners in the practice stimulating them to follow the guidelines of the Dutch College of Genral Practitioners. The primary outcome of the study is the number of antibiotic and PPI prescriptions per 1000 patients per year. THese data will be collected anonymously via pharmacies.
- Primary outcomenumber of antibiotic prescriptions per 1000 patients in the practice per year

number of PPI prescriptions per 1000 patients in the practice per year
- Secondary outcomeGeneral practitioners in the antibiotic intervention group register their own prescribing behaviour in daily routine care (anonymous patient characteristics, diagnosis, prescribing). Based on this information the rate of unnecessary prescribing (overprescribing) can be determined. Overprescribing will only be collected for the antibiotic intervention group in the year prior to the intervention and in the year after the intervention, via registration forms filled in by the practitioners.
- Timepointsbase-line (year prior to the intervention)
1: year after the intervenion
2: second year after the intervention
3: third year after the intervention
These data will be collected for periodes of 12 months anonymously via pharmacies.
- Trial web sitenone
- statusinclusion stopped: follow-up
- CONTACT for SCIENTIFIC QUERIESDr. A.W. Velden, van der
- Sponsor/Initiator Julius Center for Health Sciences and Primary Care
- Funding
(Source(s) of Monetary or Material Support)
ZON-MW, The Netherlands Organization for Health Research and Development
- PublicationsN/A
- Brief summaryAntibiotic overuse is a growing public health problem. Interventions to optimise antibiotic prescribing by practitioners have shown effectiveness. This effect however diminshed in time. With an educational intervention for general practitioners embedded within the practice organisation of the Dutch College of Genral Practitioners (defining targets for improvements) we aim to achieve a longer term positive effect on antibitoic prescribing quality.
- Main changes (audit trail)
- RECORD3-okt-2013 - 19-nov-2013

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