search  
 


Home

Who are we?

Why
register?


Signup for
registration


Online registration

Log in to register
your trial


Search a trial

NRT en CCMO

Contact

NEDERLANDS





MetaRegister
van CCT (UK)


ISRCTN-Register
van CCT (UK)


Comparing IVF results when using two commercially available culture media (part 2) - a multi-centre randomized controlled trial


- candidate number19411
- NTR NumberNTR4774
- ISRCTNISRCTN no longer applicable
- Date ISRCTN created
- date ISRCTN requested
- Date Registered NTR9-sep-2014
- Secondary IDsNL50712.000.14 toetsingonline
- Public TitleComparing IVF results when using two commercially available culture media (part 2) - a multi-centre randomized controlled trial
- Scientific TitleComparing IVF results when using two commercially available culture media (part 2) - a multi-centre randomized controlled trial
- ACRONYMMEDIUM2
- hypothesisTo investigate whether the use of G5-medium for the in vitro culture of human preimplantation embryos leads to an improved live birth rate per patient as compared to the use of CSC-medium.
- Healt Condition(s) or Problem(s) studiedInfertility, Subfertility, IVF
- Inclusion criteriaSubfertile couples undergoing their first IVF (in vitro fertilization) or ICSI (intracytoplasmatic sperm injection) treatment ever or after a previous pregnancy.
- Exclusion criteria1. Couples undergoing a PGD cycle;
2. Couples for which IVF is used to prevent the transmission of HIV;
3. Couples undergoing a modified natural cycle.
4. Couples undergoing PESA or TESE
5. Patients requiring gestational surrogacy
- mec approval receivedno
- multicenter trialyes
- randomisedyes
- masking/blindingDouble
- controlActive
- groupParallel
- Type2 or more arms, randomized
- Studytypeintervention
- planned startdate 1-jan-2015
- planned closingdate1-jan-2018
- Target number of participants1980
- InterventionsOvarian hyperstimulation, oocyte retrieval and oocyte fertilization will be performed using standard procedures. In the experimental arm, all oocytes and resulting embryos will be cultured in G5-medium and in the control arm, oocytes and resulting embryos will be cultured in CSC-medium.
- Primary outcomeLive birth rate per patient
- Secondary outcomeEmbryo quality, clinical pregnancy rate, ongoing pregnancy rate, miscarriage rate, birth weight and percentage of children with congenital abnormalities
- TimepointsThe duration of the study is three years.
- Trial web site
- statusplanned
- CONTACT FOR PUBLIC QUERIES A. Montfoort, van
- CONTACT for SCIENTIFIC QUERIES A. Montfoort, van
- Sponsor/Initiator Maastricht University Medical Center (MUMC+)
- Funding
(Source(s) of Monetary or Material Support)
Nuts/Ohra
- Publications
- Brief summaryThis study investigates whether the use of G5-medium for the in vitro culture of human preimplantation embryos leads to an improved live birth rate per patient as compared to the use of CSC-medium.
- Main changes (audit trail)
- RECORD9-sep-2014 - 27-sep-2014


  • Indien u gegevens wilt toevoegen of veranderen, kunt u een mail sturen naar nederlands@trialregister.nl