search  
 


Home

Who are we?

Why
register?


Signup for
registration


Online registration

Log in to register
your trial


Search a trial

NRT en CCMO

Contact

NEDERLANDS





MetaRegister
van CCT (UK)


ISRCTN-Register
van CCT (UK)


Online prevention of anxiety and depression in adolescents - Phase II.


- candidate number20137
- NTR NumberNTR4850
- ISRCTNISRCTN no longer applicable
- Date ISRCTN created
- date ISRCTN requested
- Date Registered NTR14-okt-2014
- Secondary IDs200210010 ZonMw 
- Public TitleOnline prevention of anxiety and depression in adolescents - Phase II.
- Scientific Title"Always look on the bright side of life": Increasing emotional resilience in adolescents by training cognitive processes to prevent anxiety and depression - Phase II
- ACRONYM
- hypothesisThe aim of the current study is to test whether online training of a positive attentional bias or positive interpretation bias is successful in increasing resilience, reducing internalizing symptoms and preventing clinical disorders (anxiety/depression) in a sample of vulnerable adolescents (with heightened anxiety/depressive symptoms).
- Healt Condition(s) or Problem(s) studiedAnxiety, Depression, Adolescents, Prevention
- Inclusion criteria1. Scolars in 1st to 6th grade of high school (12-18 years)
2. VMBO, HAVO or VWO
3. Parental consent
4. Heightened symptoms: SCARED (Screen for Child Anxiety Related Emotional Disorders) >26
and/or
CDI (Children's Depression Inventory)>11
- Exclusion criteriaEduction level below regular VMBO/special education.
- mec approval receivedyes
- multicenter trialno
- randomisedyes
- masking/blindingDouble
- controlPlacebo
- groupParallel
- Type2 or more arms, randomized
- Studytypeintervention
- planned startdate 8-sep-2014
- planned closingdate30-sep-2015
- Target number of participants300
- InterventionsThere are 5 training conditions, consisting of 8 15-minute sessions of online computer training (twice a week).
1. Visual search attention bias training
2. Visual search placebo training
3. Interpretation bias training word-fragment
4. Interpretation bias training word-picture
5. Interpretation bias placebo training

Furthermore, there is one test-retest/monitoring condition, with no training.
- Primary outcome1. Self-reported anxiety: Screen for Child Anxiety Related Emotional Disorders (SCARED, Birmaher et al., 1999);
2. Self-reported depression: Child Depression Inventory (CDI, Kovacs, 1992).
- Secondary outcome1. Rosenberg self-esteem scale (RSES, Rosenberg, 1965);
2. Parent report on internalizing and externalizing problems: Strengths and Difficulties Questionnaire - child and parent version (SDQ, Goodman, 1997);
3. Perseverative Thinking Questionnaire (PTQ, Ehring et al., 2011);
4. Quality of Life (EQ-5D-Y, Wille et al., 2010);
5. Emotional response to social stress-task;
6. Attentional bias and interpretation bias to see whether the training was successful in changing these processes;
7. Health related costs to assess cost-effectiveness.
8. Evaluation questionnaire/client satisfaction
- TimepointsAssessments at pre-training, post-training and 3 and 6 months follow-up.
- Trial web site
- statusstopped: trial finished
- CONTACT FOR PUBLIC QUERIESMSc. E.L. Voogd, de
- CONTACT for SCIENTIFIC QUERIESDr. E. Salemink
- Sponsor/Initiator University of Amsterdam (UvA)
- Funding
(Source(s) of Monetary or Material Support)
ZON-MW, The Netherlands Organization for Health Research and Development
- PublicationsDe Voogd, E.L., Wiers, R.W., Prins, P.J.M., & Salemink, E. (2014). Visual search attentional bias modification reduced social phobia in adolescents. Journal of Behavior Therapy & Experimental Psychiatry, 45, 252-259. doi: 10.1016/j.jbtep.2013.11.006
- Brief summaryBased on our previous study, NTR3950, we further test an online prevention program designed to increase emotional resilience and reduce and prevent anxiety and depression symptoms in adolescents. Participants (300) are recruited on high schools, selected on heightened anxiety/depressive symptoms and randomly assigned to one of 6 conditions (3 active trainings, 2 placebo training, 1 monitoring). Training focuses on attention and interpretation biases. Anxiety and depression symptoms and secondary outcome measures are assessed at pre- and post-training and 3 and 6 months follow-up.
- Main changes (audit trail)1-dec-2014: Cut-off scores of inclusion criterium 4 changed due to limited inclusion. New cut-off scores:
SCARED (Screen for Child Anxiety Related Emotional Disorders) >16 and/or CDI (Children's Depression Inventory) > 7 - AB
- RECORD14-okt-2014 - 6-dec-2015


  • Indien u gegevens wilt toevoegen of veranderen, kunt u een mail sturen naar nederlands@trialregister.nl