search  
 


Home

Who are we?

Why
register?


Signup for
registration


Online registration

Log in to register
your trial


Search a trial

NRT en CCMO

Contact

NEDERLANDS





MetaRegister
van CCT (UK)


ISRCTN-Register
van CCT (UK)


Cardiologic prophylaxis for Contrast Induced Nephropathy (CarCIN-trial)


- candidate number21178
- NTR NumberNTR5014
- ISRCTNISRCTN no longer applicable
- Date ISRCTN created
- date ISRCTN requested
- Date Registered NTR19-dec-2014
- Secondary IDsNL50955.018.14 
- Public TitleCardiologic prophylaxis for Contrast Induced Nephropathy (CarCIN-trial)
- Scientific TitleCardiologic prophylaxis for Contrast Induced Nephropathy (CarCIN-trial)
- ACRONYMCarCIN-trial
- hypothesis
- Healt Condition(s) or Problem(s) studiedContrast Induced Nephropathy , Aortic valve stenosis
- Inclusion criteria- Patient is planned for Contrast enhanced CT and/or TAVI-procedure
- eGFR < 60 ml/min/1.73m^2
- written informed consent
- Exclusion criteria- M. Kahler / M. Waldenström -
- mec approval receivedyes
- multicenter trialno
- randomisedyes
- masking/blindingNone
- controlActive
- groupParallel
- Type2 or more arms, randomized
- Studytypeintervention
- planned startdate 1-jan-2015
- planned closingdate31-dec-2015
- Target number of participants80
- InterventionsPatients will be randomised on a 1:1 ratio in two different hydration protocols:
Arm 1) 1 hour l sodiumbicarbonate (NaHCO3, 1.4%, 3 ml/kg/1hour))
or
Arm 2) a 24 hour saline (NaCl 0.9%, 1 ml/kg/hour)
- Primary outcomeMean increase in level of serum creatinine 2-5 days after contrast administration
- Secondary outcome 1) acute kidney injury defined as an increase in serum creatinine of >25% or 44 umol 2-5 days after contrast administration,
2) need for renal replacement therapy
- Timepoints
- Trial web site
- status[default]
- CONTACT FOR PUBLIC QUERIES M.S. van Mourik
- CONTACT for SCIENTIFIC QUERIESMD PhD M.M. Vis
- Sponsor/Initiator Academic Medical Center (AMC), Department of Cardiology
- Funding
(Source(s) of Monetary or Material Support)
Academic Medical Center (AMC), Department of Cardiology
- Publications
- Brief summary
- Main changes (audit trail)
- RECORD19-dec-2014 - 11-apr-2015


  • Indien u gegevens wilt toevoegen of veranderen, kunt u een mail sturen naar nederlands@trialregister.nl