search  
 


Home

Who are we?

Why
register?


Signup for
registration


Online registration

Log in to register
your trial


Search a trial

NRT en CCMO

Contact

NEDERLANDS





MetaRegister
van CCT (UK)


ISRCTN-Register
van CCT (UK)


Fluids in pediatric cardiac surgery patients


- candidate number22172
- NTR NumberNTR5225
- ISRCTNISRCTN no longer applicable
- Date ISRCTN created
- date ISRCTN requested
- Date Registered NTR11-mei-2015
- Secondary IDsP15.152 METC Leids Universitair Medisch Centrum, Leiden
- Public TitleFluids in pediatric cardiac surgery patients
- Scientific TitlePost-operative fluid intake and morbidity in pediatric cardiothoracic patients.
- ACRONYMFOKIDS
- hypothesisPediatric cardiac surgery patients with fluid ovreload (FO) by the end op the first postoperative day (POD) have poorer clinical outcomes than patients without FO in the same period.
- Healt Condition(s) or Problem(s) studiedFluid intake, Acute kidney injury, PICU length of stay, Ventilation days
- Inclusion criteriaPatients scheduled for corrective and palliative cardiac surgery.
Patients with cardiopulmonary bypass for cardiac surgery
Patients between 2 weeks and 10 years.
- Exclusion criteriaAcute surgical interrvention.
patients from dept of Neonathology
patient with preexisting renal failure or requiring renal replacement therapy (RRT)
- mec approval receivedyes
- multicenter trialno
- randomisedno
- group[default]
- TypeSingle arm
- Studytypeobservational
- planned startdate 1-jul-2015
- planned closingdate1-jul-2016
- Target number of participants300
- InterventionsNo specific interventions.
Observational studie.
- Primary outcomeDuration (time) of mechanical ventilation
- Secondary outcome1. Length of stay in Pediatric ICU
2. Length of stay in Hospital
3. Number of patients needing renal repalcement therapy
4. Use of inotropes and diuretics during surgery and admission PICU
- TimepointsFliud intake Post-operatieve day (POD) 0, POD 1, POD 2, POD 3, POD 4, POD 5, POD 6, POD 7.
- Trial web siten.a.
- statusplanned
- CONTACT FOR PUBLIC QUERIESDr. H.E Bunker-Wiersma
- CONTACT for SCIENTIFIC QUERIESDr. H.E Bunker-Wiersma
- Sponsor/Initiator Leiden University Medical Center (LUMC), Department of paediatric Intensive Care
- Funding
(Source(s) of Monetary or Material Support)
Leiden University Medical Center (LUMC) Department of paediatric Intensive Care
- Publications
- Brief summaryPediatric patients who undergo cardiopulmonary bypass are at risk for poor cardiac, pulmonary, and renal outcomes.
They are also at risk of fluid overload from cardiopulmonary bypass, which stimulates inflammation, release of antidiuretic hormone, and capillary leak. This study tested the hypothesisthat patients with fluid overload in the early postcardiopulmonary bypass period have worse outcomes than those without fluid overload.
Early postoperative fluid overload, defined as a fluid balance 5% above body weight by the end of postoperative day 1.
- Main changes (audit trail)
- RECORD11-mei-2015 - 29-jul-2015


  • Indien u gegevens wilt toevoegen of veranderen, kunt u een mail sturen naar nederlands@trialregister.nl