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Perceptual learning to reduce crowding effects in visually impaired children


- candidate number22213
- NTR NumberNTR5236
- ISRCTNISRCTN no longer applicable
- Date ISRCTN created
- date ISRCTN requested
- Date Registered NTR19-mei-2015
- Secondary IDsNL49432.091.14 CMO Arnhem-Nijmegen
- Public TitlePerceptual learning to reduce crowding effects in visually impaired children
- Scientific TitlePerceptual learning to reduce crowding effects in visually impaired children
- ACRONYM
- hypothesis-Perceptual learning can reduce foveal crowding in children with albinism and idiopathic infantile nystagmus
- Healt Condition(s) or Problem(s) studiedVisual impairment
- Inclusion criteria-Age 6-10 years
-Normal birth weight
-Birth at term
-No perinatal complications
-Normal development
-No motor or intellectual impairments
- Exclusion criteria-children with normal vision: distance visual acuity <20/25 or 0.80
-children with visual impairment: distance visual acuity <20/400 or 0.05
- mec approval receivedyes
- multicenter trialno
- randomisedyes
- masking/blindingNone
- controlActive
- groupParallel
- Type2 or more arms, non-randomized
- Studytypeintervention
- planned startdate 5-jan-2015
- planned closingdate7-jun-2015
- Target number of participants80
- InterventionsA computerized perceptual learning training will be used to reduce crowding in children with visual impairment. Children in the experimental group train with target letters surrounded by distrators and children in the control group train with isolated letters.
- Primary outcome-Crowding ratio (distance and near)
- Secondary outcome-Distance and near visual acuity (sensory component)
-Fixation stability (motor component)
-Saccade execution (motor component)
-Reading performance (cognitive aspect)
- TimepointsN.A.
- Trial web siteN.A.
- statusstopped: trial finished
- CONTACT FOR PUBLIC QUERIESDr. J. Goossens
- CONTACT for SCIENTIFIC QUERIESDr B. Huurneman
- Sponsor/Initiator Radboud University Medical Center Cognitive Neuroscience
- Funding
(Source(s) of Monetary or Material Support)
Bartiméus Stichting, ODAS
- Publications
- Brief summaryChildren with visual impairment show stronger crowding than children with normal vision; they have more difficulty identifying a suprathreshold object in the presence of clutter. Children with visual impairment also show a lag in their reading skills and longer visual search times than age-matched peers with normal vision. Recent studies demonstrate the potential prospects of perceptual learning to improve visual functions. However, it is still unclear which mechanisms are responsible for these improvements.
The main objective of this study is to determine whether perceptual learning can reduce crowding in children with visual impairment. In addition, the study aims to extent our understandings about the mechanisms that underlie crowding and perceptual learning. In order to do so, the effect of training on oculomotor, sensory and cognitive aspects will be evaluated separately.
- Main changes (audit trail)
- RECORD19-mei-2015 - 22-mei-2016


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