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Motor cortical control of antagonist muscle function in aging


- candidate number22772
- NTR NumberNTR5371
- ISRCTNISRCTN no longer applicable
- Date ISRCTN created
- date ISRCTN requested
- Date Registered NTR20-aug-2015
- Secondary IDsNL52432.042.15 METc UMCG
- Public TitleMotor cortical control of antagonist muscle function in aging
- Scientific TitleMotor cortical control of antagonist muscle function in aging
- ACRONYM
- hypothesisMotor cortical control of antagonist muscle function changes with age
- Healt Condition(s) or Problem(s) studiedOlder adults
- Inclusion criteriaHealthy younger adults aged 18 - 30 years and healthy older adults aged 65 years and older, both male and female gender, right handed based on the Edinburgh Handedness Inventory.
- Exclusion criteriaFracture in the upper extremity over the past year, neurological disorders, pregnancy, muscle or joint disorders, cardiovascular diseases, medicine known to affect nerve conduction, Epilepsy, Pacemaker, metal in the brain/skull.
- mec approval receivedno
- multicenter trialno
- randomisedno
- groupParallel
- Type2 or more arms, non-randomized
- Studytypeobservational
- planned startdate 1-sep-2015
- planned closingdate1-jul-2016
- Target number of participants28
- InterventionsRapidly flexing the wrist to a position of 20 degrees after hearing an auditory tone
- Primary outcomeThe amount of coactivation during a rapid flexion of the wrist after hearing an auditory tone
- Secondary outcomeThe corticospinal excitability indexed by the size of the motor evoked potentials (MEPs) produced by transcranial magnetic stimulation (TMS)
- TimepointsOne moment of measurement
- Trial web site
- statusplanned
- CONTACT FOR PUBLIC QUERIES T. Hortobágyi
- CONTACT for SCIENTIFIC QUERIES T. Hortobágyi
- Sponsor/Initiator University Medical Center Groningen (UMCG)
- Funding
(Source(s) of Monetary or Material Support)
University Medical Center Groningen (UMCG)
- Publications
- Brief summary
- Main changes (audit trail)
- RECORD20-aug-2015 - 26-aug-2015


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