search  
 


Home

Who are we?

Why
register?


Signup for
registration


Online registration

Log in to register
your trial


Search a trial

NRT en CCMO

Contact

NEDERLANDS





MetaRegister
van CCT (UK)


ISRCTN-Register
van CCT (UK)


Alemtuzumab or rituximab induction in ABO-incompatible kidney transplantation.


- candidate number22281
- NTR NumberNTR5384
- ISRCTNISRCTN no longer applicable
- Date ISRCTN created
- date ISRCTN requested
- Date Registered NTR2-jun-2015
- Secondary IDsMEC-2015-246 
- Public TitleAlemtuzumab or rituximab induction in ABO-incompatible kidney transplantation.
- Scientific TitleAlemtuzumab or rituximab induction in ABO-incompatible kidney transplantation.
- ACRONYM
- hypothesisAlemtuzumab induction therapy in ABOi kidney transplantation lowers the incidence of cellular-mediated BPAR compared to rituximab induction, without affecting the number of antibody-mediated rejections.
- Healt Condition(s) or Problem(s) studiedRenal transplant , ABO-incompatible
- Inclusion criteriaRecipients of an ABO-incompatible kidney transplant aged 18 years or older.
- Exclusion criteriaRecipients of an ABO-compatible kidney allograft.
- mec approval receivedyes
- multicenter trialno
- randomisedno
- groupFactorial
- Type2 or more arms, non-randomized
- Studytypeobservational
- planned startdate 30-apr-2015
- planned closingdate1-jul-2017
- Target number of participants100
- Interventionsobservational study
- Primary outcome- To compare the number of biopsy-proven acute rejections (BPAR) within three months after ABOi kidney transplantation in rituximab versus alemtuzumab treated patients.
- Secondary outcome- To compare infectious complications after ABOi kidney transplantation in rituximab versus alemtuzumab treated patients.
- T compare renal function one year after ABOi kidney transplantation in rituximab versus alemtuzumab treated patients.
- Timepointst=0
t=3 months
t=12 months
- Trial web site
- statusopen: patient inclusion
- CONTACT FOR PUBLIC QUERIES A.E. Weerd, de
- CONTACT for SCIENTIFIC QUERIES A.E. Weerd, de
- Sponsor/Initiator Erasmus Medical Center
- Funding
(Source(s) of Monetary or Material Support)
Erasmus Medical Center
- Publications
- Brief summary
- Main changes (audit trail)
- RECORD2-jun-2015 - 13-okt-2015


  • Indien u gegevens wilt toevoegen of veranderen, kunt u een mail sturen naar nederlands@trialregister.nl