search  
 


Home

Who are we?

Why
register?


Signup for
registration


Online registration

Log in to register
your trial


Search a trial

NRT en CCMO

Contact

NEDERLANDS





MetaRegister
van CCT (UK)


ISRCTN-Register
van CCT (UK)


Posttraumatic osteoarthritis following perilunate (fracture) dislocations


- candidate number22788
- NTR NumberNTR5425
- ISRCTNISRCTN no longer applicable
- Date ISRCTN created
- date ISRCTN requested
- Date Registered NTR24-aug-2015
- Secondary IDsNL52111.042.15 
- Public TitlePosttraumatic osteoarthritis following perilunate (fracture) dislocations
- Scientific TitlePosttraumatic osteoarthritis following perilunate dislocations and perilunate fracture dislocations in young patients and the correlation with subjective and objective outcome measures. A descriptive cohort study
- ACRONYM
- hypothesisTo determine the prevalence of posttraumatic osteoarthritis following a PLD-PLFDs in a cohort of young non-osteoporotic patients and correlation with objective and subjective outcome measures.
- Healt Condition(s) or Problem(s) studiedPost-traumatic arthritis
- Inclusion criteriaAll patients treated in the period 1996 until 2014 in the University Medical Center Groningen for a PLD-PLFD
- Men between the ages of 18 - 50 years and women between the ages of 18 - 40 years at the time of injury (no clinical osteoarthritis according to current available information in the literature)
- Written informed consent
- Mentally competent
- Exclusion criteriaPreexistent osteoarthritis of the hand or preexistent declined function of the hand or wrist according to the patient
- ASA III-V patients or other contra-indications for surgical treatment at the time of injury. These patients are not able to receive the most optimal treatment and thus altered outcome measures can be expected
- No permanent residency (in the Netherlands)
- Co-morbidity that may influence the outcomes, such as neurological of rheumatic disorders influencing arm function.
- Insufficient control of the Dutch language.
- No informed consent
- Osteoporosis known from medical history
- Pregnant women
- mec approval receivedyes
- multicenter trialno
- randomisedno
- group[default]
- Type[default]
- Studytypeobservational
- planned startdate 1-aug-2015
- planned closingdate8-aug-2016
- Target number of participants30
- InterventionsNo intervention.
Questionnaires: PRWE, DASH, SF-36 and MHQ.
X-rays of both hands. Range of motion test and grip strength test by a certified handphysician
- Primary outcomeThe prevalence of posttraumatic osteoarthritis.
- Secondary outcomePatient reported functional outcomes objectified with the PRWE, DASH, SF-36 and MHQ.
Objective outcomes: X-rays, range of motion, grip strength.
- TimepointsObservational study, there will be various timepoints.
- Trial web site
- statusplanned
- CONTACT FOR PUBLIC QUERIESDrs. C.M. Lameijer
- CONTACT for SCIENTIFIC QUERIESDrs. C.M. Lameijer
- Sponsor/Initiator University Medical Center Groningen (UMCG)
- Funding
(Source(s) of Monetary or Material Support)
Fonds de Gavere
- Publications
- Brief summary The development of posttraumatic osteoarthritis (PA) following perilunate dislocations and perilunate fracture dislocations (PLD-PLFDs) has been described. Direct and indirect joint impact loading, soft tissue injuries, joint dislocation and intra-articular fractures, increase the risk of progressive joint degeneration that cause PA. It is though posttraumatic osteoarthritis develops less in younger patients. However, it might be more invalidating for a young non-osteoporotic patient to develop posttraumatic osteoarthritis and loss of function following PLD-PLFD than for an older patient. The extent of the loss of function can be objectified using functional measures, such as range of motion and grip strength. Subjective measures to objectify loss of function as experienced by the patient can be performed using validated questionnaires. In this study, the prevalence of posttraumatic osteoarthritis following a PLD-PLFD in young patients is determined. Also, the question arises what the correlation between objective and subjective outcome measures is following a PLD-PLFD in young patients.
- Main changes (audit trail)
- RECORD24-aug-2015 - 4-nov-2015


  • Indien u gegevens wilt toevoegen of veranderen, kunt u een mail sturen naar nederlands@trialregister.nl