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van CCT (UK)

van CCT (UK)

"The Medical Emergency Team (MET): Hospital Outcomes after a Day" study

- candidate number23533
- NTR NumberNTR5535
- ISRCTNISRCTN no longer applicable
- Date ISRCTN created
- date ISRCTN requested
- Date Registered NTR23-dec-2015
- Secondary IDs2015.91 METC WOAC Albert Schweitzer Hospital Dordrecht
- Public Title"The Medical Emergency Team (MET): Hospital Outcomes after a Day" study
- Scientific Title"The Medical Emergency Team (MET): Hospital Outcomes after a Day" study
- hypothesisPatients subject to MET review have a high in-hospital mortality (20%). Thus, understanding the outcome of patients within the first 24hr of MET review is important in developing quality improvement and interventional studies to reduce this mortality. The present study will provide an initial analysis of these outcomes, and the inter-hospital variability of them.
- Healt Condition(s) or Problem(s) studiedMedical Emergency Team
- Inclusion criteriaParticipants will include all adult clinically admitted patients, who are subject to MET review over a month period in the participating hospitals.
- Exclusion criteria< 18 years
- mec approval receivedyes
- multicenter trialyes
- randomisedno
- group[default]
- TypeSingle arm
- Studytypeobservational
- planned startdate 1-feb-2016
- planned closingdate29-feb-2016
- Target number of participants1000
- InterventionsCollection of patient data at the time of and 24 hours following MET review.
- Primary outcome* 24-hour mortality
* number of intensive care unit (ICU) admissions
* number of urgent transfer to the operating room (OR)
* number of use of limitations of therapy orders
- Secondary outcome* 30-days mortality
- TimepointsCollection of patient data at the time of and 24 hours following MET review.
- Trial web sitenone
- statusplanned
- Sponsor/Initiator Jonathan Barnard-Smith, Central Manchester University Hospitals, Daryl Jones, Austin Hospital, Rinaldo Bellomo, Austin Hospital, Geoff Lighthall, Stanford University Hospital, Lesley Durham, Director North of England Critical Care Operational Delivery Network, John Welch, University College Hospital, Chris Subbe, Ysbyty Gwynedd, Ralph So, Albert Schweitzer Hospital
- Funding
(Source(s) of Monetary or Material Support)
Self Funding
- Publications-
- Brief summaryPatients admitted to hospital wards have increasingly complex conditions and multiple co-morbidities. Rapid Response Teams (RRTs) and similar services have been introduced in order to identify, review and treat at-risk and deteriorating ward patients in an attempt to reduce serious adverse events, cardiac arrests, and unplanned admissions to the intensive care unit (ICU).

Most of the literature related to RRT calls evaluates the effects of introducing a RRT on the outcomes of all hospitalized patients. Much less information exists on the epidemiology of the group of patients subject to RRT review. A small number of studies have assessed the triggers for RRT calls. Less information exists on the interventions performed by the RRT, and the immediate outcomes of patients after RRT review. There is also no information on how patient outcomes after RRT review may vary between countries. This information is important, as patients subject to RRT review have an in-hospital mortality rate in the order of 20%.

The purpose of this study was to examine the short-term (24 hours) outcome of patients triggering RRT review. Specifically, we examined the proportion of patients who died, were admitted to ICU or were transferred to the operating room. Moreover, we assessed whether there were new limitations of medical treatment order were applied, and whether the patientís physiological condition had improved or not. Finally, we assessed variations in such outcomes between different hospitals internationally.

Countries: UK, the Netherlands, Danmark, USA, Australia
- Main changes (audit trail)
- RECORD23-dec-2015 - 31-jan-2016

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