search  
 


Home

Who are we?

Why
register?


Signup for
registration


Online registration

Log in to register
your trial


Search a trial

NRT en CCMO

Contact

NEDERLANDS





MetaRegister
van CCT (UK)


ISRCTN-Register
van CCT (UK)


De effecten van 4 weken training en eiwitsupplementen op spierkracht, spiermassa en conditie in een ongetrainde 55+ populatie


- candidate number23974
- NTR NumberNTR5701
- ISRCTNISRCTN no longer applicable
- Date ISRCTN created
- date ISRCTN requested
- Date Registered NTR16-feb-2016
- Secondary IDsMETC-WU (15/35) 
- Public TitleDe effecten van 4 weken training en eiwitsupplementen op spierkracht, spiermassa en conditie in een ongetrainde 55+ populatie
- Scientific TitleThe effects of short-term exercise and protein supplementation on muscle strength, muscle mass and physical fitness in untrained older adults
- ACRONYMSTEP
- hypothesisShort-term exercise and protein supplementation enhances muscle strength, mass and physical fitness in a group of untrained men and women aged 55-75 years.
- Healt Condition(s) or Problem(s) studiedMuscle strength, Older adults
- Inclusion criteria- Aged 55 to 75 years.
- Not meeting the Dutch Norm for Health-enhancing Physical Activity ('Nederlandse Norm Gezond Bewegen').
- No participation in any structured or regular exercise training programs for the last 3 months.
- Exclusion criteria- Allergic or sensitive for milk proteins, or lactose intolerant.
- Diagnosed with renal insufficiency.
- On a diet which affects protein intake (i.e. advices of an increase, decrease or type of protein (intake)).
- Having known contraindications for exercise.
- Diagnosed with cancer for which currently treated.
- Having a contraindication to MRI scanning (including, but not limited to):
o pacemakers and defibrillators
o intraorbital or intraocular metallic fragments
o ferromagnetic implants
o claustrophobia
- Participation in another intervention trial.
- Unable to understand Dutch.
- mec approval receivedyes
- multicenter trialno
- randomisedno
- group[default]
- TypeSingle arm
- Studytypeintervention
- planned startdate 1-mrt-2016
- planned closingdate1-aug-2016
- Target number of participants18
- InterventionsAll subjects will receive a 4 week intervention program consisting of:
1) an exercise program (combination of resistance and aerobic exercises during supervised exercise sessions, and a home-based advice)
2) protein supplementation.
- Primary outcomeThe primary outcome of this study is the change in isometric quadriceps strength (Biodex).
- Secondary outcomeSecondary parameters are changes in quadriceps muscle mass (MRI and ultrasound), handgrip strength (dynamometer), power of the lower limb (chair rise time test), physical fitness (Åstrand-Rhyming test), habitual physical activity (accelerometer) and daily protein intake (24h recall questionnaire).
- TimepointsParameters are assessed at baseline, 2 weeks and 4 weeks.
- Trial web sitenot applicable
- statusopen: patient inclusion
- CONTACT FOR PUBLIC QUERIESMSc Margot de Regt
- CONTACT for SCIENTIFIC QUERIESMSc Margot de Regt
- Sponsor/Initiator Ziekenhuis Gelderse Vallei
- Funding
(Source(s) of Monetary or Material Support)
Eat2Move
- Publications
- Brief summaryRationale and objective:
The aging process and physical inactivity are both clearly linked to low muscle mass, muscle strength and physical fitness. Long-term exercise programs in combination with protein supplementation show improvements in muscle function. However, in some circumstances such as prior surgery, time available to improve person’s muscle function and physical fitness is limited to a few weeks. Therefore, the present study aims to investigate whether an improvement in muscle strength, muscle mass and physical fitness can be achieved within 4 weeks of exercise and protein supplementation in a group of untrained men and women aged 55-75 years.

Study design: Single group repeated measures design.

Study population: 18 untrained men and women aged 55 to 75 years who do not meet the Dutch Norm for Health-enhancing Physical Activity ('Nederlandse Norm Gezond Bewegen').

Intervention: 4 weeks of exercise and protein supplementation

Main study parameters: Changes in quadriceps strength, quadriceps muscle mass, handgrip strength, power of the lower limb, physical fitness, habitual physical activity and daily protein intake. Parameters are assessed at baseline, 2 weeks and 4 weeks.
- Main changes (audit trail)
- RECORD16-feb-2016 - 16-apr-2016


  • Indien u gegevens wilt toevoegen of veranderen, kunt u een mail sturen naar nederlands@trialregister.nl