search  
 


Home

Who are we?

Why
register?


Signup for
registration


Online registration

Log in to register
your trial


Search a trial

NRT en CCMO

Contact

NEDERLANDS





MetaRegister
van CCT (UK)


ISRCTN-Register
van CCT (UK)


IgG4-associated cholangitis after resection for presumed perihilar cholangiocarcinoma


- candidate number27214
- NTR NumberNTR6461
- ISRCTNISRCTN no longer applicable
- Date ISRCTN created
- date ISRCTN requested
- Date Registered NTR15-mei-2017
- Secondary IDs2016-134 METC AMC
- Public TitleIgG4-associated cholangitis after resection for presumed perihilar cholangiocarcinoma
- Scientific TitleIgG4-associated cholangitis after resection for presumed perihilar cholangiocarcinoma
- ACRONYM
- hypothesisIgG4-associated cholangitis mimicks perihilar cholangiocarcinoma, resulying in patients being resected for benign disease
- Healt Condition(s) or Problem(s) studiedIgG4-associated cholangitis
- Inclusion criteriaResection for presumed perihilar cholangiocarcinoma
- Exclusion criterianone
- mec approval receivedyes
- multicenter trialno
- randomisedno
- group[default]
- TypeSingle arm
- Studytypeobservational
- planned startdate 1-jan-2016
- planned closingdate1-okt-2017
- Target number of participants323
- InterventionsNone
- Primary outcomeIncidence of IgG4-associated cholangitis in patients resected for presumed PHC
- Secondary outcomeEvaluation of active disease with sIgG4 and qPCR test for IgG4/IgG mRNA ratio
- Timepoints-re-evaluation resection specimens
-clinical re-evaluation symptoms and serummarkers
- Trial web site
- statusopen: patient inclusion
- CONTACT FOR PUBLIC QUERIESMD, PhD candidate Eva Roos
- CONTACT for SCIENTIFIC QUERIESMD, PhD candidate Eva Roos
- Sponsor/Initiator Academic Medical Center (AMC), Amsterdam
- Funding
(Source(s) of Monetary or Material Support)
Academic Medical Center (AMC)
- Publications
- Brief summaryOur aim is to assess the incidence of Immunoglobulin G4-associated cholangitis (IAC) in patients resected for presumed perihilar cholangiocarcinoma (PHC). All patients that underwent resection for presumed PHC at our institution between 1984 and 2015 were included. Benign histological specimens were re-evaluated by a pathologist and scored according to the international pathological consensus criteria for IgG4-RD. Patients with benign disease who were still alive were re-evaluated to assess IgG4 serum levels and IgG4/IgG RNA ratio to detect activity of IAC.
- Main changes (audit trail)
- RECORD15-mei-2017 - 3-jul-2017


  • Indien u gegevens wilt toevoegen of veranderen, kunt u een mail sturen naar nederlands@trialregister.nl