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Nitrate and muscle performance


- candidate number27362
- NTR NumberNTR6507
- ISRCTNISRCTN no longer applicable
- Date ISRCTN created
- date ISRCTN requested
- Date Registered NTR8-jun-2017
- Secondary IDsEACO 56.02/17 
- Public TitleNitrate and muscle performance
- Scientific TitleThe impact of dietary nitrate supplementation on muscle strength and muscle endurance performance.
- ACRONYM
- hypothesisWe hypothesize that dietary nitrate supplementation improves muscle strength and muscle endurance performance.
- Healt Condition(s) or Problem(s) studiedDietary nitrate, Exercise performance
- Inclusion criteria-Healthy male
-Recreationally active (0.5 8 h of sport activities per week on a non-competitive base)
-18-40 years
- Exclusion criteria-Obesity (BMI >30 kg/m2)
-Injury preventing maximal exercise performance
-Smoking
-Current use of dietary nitrate supplements
-Medication interfering with nitric oxide metabolism, or medication known to affect physical or mental performance
- mec approval receivedno
- multicenter trialno
- randomisedyes
- masking/blindingDouble
- controlPlacebo
- groupCrossover
- Type2 or more arms, randomized
- Studytypeintervention
- planned startdate 1-apr-2017
- planned closingdate1-aug-2017
- Target number of participants15
- InterventionsDietary nitrate will be ingested as beetroot juice. The intervention comprises a 6-day supplementation period with either beetroot juice (140 mL daily) or nitrate-depleted beetroot juice (placebo; 140 mL daily). After ingestion of the last bolus of beetroot or placebo juice, counter movement jump performance, maximal strength and muscular endurance will be assessed. Both experimental periods will be separated by a wash-out period of at least 1 week.
- Primary outcome-Counter movement jump performance
-Maximal isometric voluntary contraction
-Maximal isokinetic voluntary contraction
-Isokinetic muscle endurance performance
- Secondary outcome-Plasma nitrate and nitrite
- Timepoints-Exercise testing will be performed after a 6-day supplementation period with beet root juice or placebo.
- Trial web sitehttp://blog.han.nl/hansportnutrition/
- statusopen: patient inclusion
- CONTACT FOR PUBLIC QUERIES Jan-Willem van Dijk
- CONTACT for SCIENTIFIC QUERIES Jan-Willem van Dijk
- Sponsor/Initiator HAN University of Applied Sciences
- Funding
(Source(s) of Monetary or Material Support)
EAT2MOVE
- Publications
- Brief summary
- Main changes (audit trail)
- RECORD8-jun-2017 - 11-jul-2017


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