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van CCT (UK)

van CCT (UK)

Eye Movement Desensitization and Reprocessing in Older Adults

- candidate number27552
- NTR NumberNTR6569
- ISRCTNISRCTN no longer applicable
- Date ISRCTN created
- date ISRCTN requested
- Date Registered NTR14-jul-2017
- Secondary IDs15-N-203 METC Zuyderland Zuyd
- Public TitleEye Movement Desensitization and Reprocessing in Older Adults
- Scientific TitleFeasibility of Eye Movement Desensitization and Reprocessing in Older Adults with Posttraumatic Stress Disorder compared to Adults and Impact of Comorbid Personality Disorders and Cognitive Functioning.
- hypothesis1) Feasibility of EMDR in older adults (age 60+) is comparable to younger adults (age 20-60);
2) EMDR treatment of PTSD results in improvement of PDs and improvement of cognitive functioning.
3) Somatic and psychiatric comorbidity are negatively associated to the feasibility size of EMDR .
- Healt Condition(s) or Problem(s) studiedPost-traumatic stress disorder,, Cognitive functioning, Personality disorder
- Inclusion criteria-Patients with PTSD and eligible for psychiatric treatment according to routine clinical standards (according to clinical psychiatric evaluation by a psychiatrist)
-Intention to be treated and participate with treatment
-Written informed consent
- Exclusion criteria -Age < 18 years
-Major medical or psychiatric conditions that may interfere with the study procedures: cancer, cerebrovascular disorders, organic psychiatric syndromes, active drug abuse, mental retardation (IQ<70), severe stages of dementia and other neurodegenerative disorders (MMSE<21). Psychopathology will be assesses by M.I.N.I., a psychiatric interview.
-Any condition which in the opinion of the (co-) investigator might interfere with the evaluation of the study objectives.
- mec approval receivedyes
- multicenter trialyes
- randomisedyes
- masking/blindingNone
- controlActive
- groupParallel
- TypeSingle arm
- Studytypeintervention
- planned startdate 1-okt-2016
- planned closingdate1-okt-2020
- Target number of participants60
- InterventionsEMDR
- Primary outcomePTSS klachten (CAPS, PSS-sr, BSI)
Persoonlijkheidsfunctioneren (SIPP-sf)
Cognitief functioneren (Stroop , VLT , WDST, digit span task, BPS-O)
Algehele fysieke kwetsbaarheid (GFI, EQ)
- Secondary outcome- Scores on Recent Traumatic Events Scale: discrete variable
- Scores on Childhood Traumatic Events Scale: discrete variable
Secondary outcome variables are:
- Traumatic childhood experiences, severity and kind of experiences
- Traumatic experiences in later life, severity and kind of experiences
- Timepoints0 months/intake: (RTES/CTES, CAPS, MINI, MMSE, Stroop, VLT, WDST, digit span task, BPS-O, SCID II, SIPP-sf, PSS-sr, BSI, GFI, EQ)
3 months (PSS-sr, BSI, SIPP-sf, CAPS)
6 months (PSS-sr, BSI, SIPP-sf, CAPS)
9 months (or by 3 or by 6 months when therapy has been done in 3 or 6 months) (CAPS, MINI, MMSE, Stroop, VLT, WDST, BPS-O, digit span task, SCID II, SIPP-sf, PSS-sr, BSI, GFI, EQ)
- Trial web site-
- statusrecruitement status not public
- Sponsor/Initiator RINO Zuid
- Funding
(Source(s) of Monetary or Material Support)
- Publications
- Brief summaryTraumatic life events can result in severe psychiatric symptoms of which the Post Traumatic Stress Disorder (PTSD) is the most prevalent. It is still not fully resolved why some people develop PTSD after trauma and others do not. Moreover, PTSD in older adults may be difficult to recognize due to the complicated presentation. Often masked by other psychiatric (including Personality Disorders (PDs)) and/ or somatic disorders. Substantial disability due to comorbid somatic conditions and psychiatric disorders are also associated with PTSD. Comorbid (PDs) may indicate some predisposed vulnerability and influence treatment effect. Furthermore cohort properties such as underreporting psychological symptoms, long time to distant trauma and increase of functional losses and stressors may interfere with adequate recognition. Besides, dysregulated cognitive functioning is associated with impaired recovery following trauma. Since cognitive impairment is common in PTSD and elderly it may influence treatment effect. Therefore, the relationship between treatment effect, PDs and cognitive functions needs further investigation. Eye Movement Desensitization Reprocessing (EMDR) has been proved as a powerful treatment for adults with PTSD. In this study EMDR feasibility will be investigated related to older adults with PTSD and compared to adults with PTSD.
- Main changes (audit trail)
- RECORD14-jul-2017 - 4-aug-2017

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