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van CCT (UK)

van CCT (UK)

Strong teens and resilient minds: Depression and Suicide Prevention in Secondary Education

- candidate number27713
- NTR NumberNTR6622
- ISRCTNISRCTN no longer applicable
- Date ISRCTN created
- date ISRCTN requested
- Date Registered NTR3-aug-2017
- Secondary IDs2017-3395; NL61559.091.17 CMO Regio Arnhem-Nijmegen
- Public TitleStrong teens and resilient minds: Depression and Suicide Prevention in Secondary Education
- Scientific TitleEvaluation of a multimodal school-based depression and suicide prevention program among Dutch adolescents: a cluster-randomized controlled trial
- hypothesisSince 2010, suicide is the most important cause of mortality in youth aged 15 to 29 years, in the Netherlands. An important risk factor for suicidal behaviours in adolescents is depression. Once adolescents have developed depressive symptoms, they are also at risk for adult depression. As a result of increasing numbers of adolescents that suffer from depression and suicidal behaviour health care policies should focus on preventive interventions that aim to reduce these numbers. We will test and, if effective, implement a multimodal stepped-prevention program in 12-15 year olds in secondary schools in the Netherlands. The comprehensive program consists of four components: early screening and detection, gatekeepers training, universal suicide prevention, and indicated depression prevention. It is expected that participants in the intervention group will show a greater decline in suicidal behaviour and depressive symptoms during follow-up than the participants in the control group.
- Healt Condition(s) or Problem(s) studiedSuicide attempt, Depression
- Inclusion criteriaadolescents are aged between 11-15 years old,
sufficient knowledge of the Dutch language
- Exclusion criteriaabsence of studentís permission,
absence of parental permission
- mec approval receivedyes
- multicenter trialno
- randomisedyes
- masking/blindingNone
- controlActive
- groupParallel
- Type2 or more arms, randomized
- Studytypeintervention
- planned startdate 1-sep-2017
- planned closingdate31-okt-2021
- Target number of participants1844
- InterventionsScreening,
Gatekeeperstraining for school mentors
universal preventive intervention focused on depression stigma in the form of a serious game
indicated preventive intervention focused on depressive symptoms in the form of a cbt-based skills training
- Primary outcomeVOZZ suicidal behaviour (T0-T5)
- Secondary outcomeVOZZ-Screen suicidal behaviour risk (screening)
CDI2 depressive symptoms (screening - T5)
ADIS-Cpresence of a clinical depression (T2)
DSS personal depression stigma (T0-T5)
DSS perceived depression stigma (T0)
PSWQ worry (T0-T5)
PMS mastery (T0-T5)
Top Problems life events (T0-T5)
social connectedness (T0-T5)
FMPS perfectionism (T0)
school-related factors (screening-T5)
demographic variables (T0)
- TimepointsScreening
T0; baseline
T1; mid-intervention
T2; post-intervention
T3; 6-month follow-up
T4; 12-month follow-up
T5; 24-month follow-up
- Trial web site
- statusplanned
- CONTACT for SCIENTIFIC QUERIESProf. Dr. Rutger C.M.E. Engels
- Sponsor/Initiator GGZ Oost Brabant
- Funding
(Source(s) of Monetary or Material Support)
counties: Asten, Someren, Laarbeek, Geldrop-Mierlo, Helmond, Deurne, Gemert-Bakel
- Publications
- Brief summaryThe current study examines the effectiveness of the multimodal prevention program for suicidality and depressive symptoms using a cluster randomized trial. This includes a combination of preventive interventions, such as (1) early detection and identification with subsequent clinical referral, (2) a safety net consisting of gatekeepers at school, (3) universal prevention focusing on stigma reduction, (4) screening to identify adolescents that have elevated signs of the most important risk factor for suicidal behaviour, i.e. depression and subsequent indicated prevention for screen-positive adolescents.The primary outcome will be suicidal behaviours, i.e. suicidal thoughts and plans, deliberate self-harm and suicide attempts as measured with the VOZZ. Secondary study outcomes are depressive feelings, worry, perfectionism, mastery, stigma and academic functioning. Measurements of primary and secondary outcomes will be conducted in intervention and control condition at baseline, mid-intervention, post-intervention, and at 6-, 12- and 24-month follow-up
- Main changes (audit trail)
- RECORD3-aug-2017 - 20-aug-2017

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