search  
 


Home

Who are we?

Why
register?


Signup for
registration


Online registration

Log in to register
your trial


Search a trial

NRT en CCMO

Contact

NEDERLANDS





MetaRegister
van CCT (UK)


ISRCTN-Register
van CCT (UK)


Evaluation of boiled vs raw eggs for stimulating post-exercise muscle protein synthesis


- candidate number27832
- NTR NumberNTR6694
- ISRCTNISRCTN no longer applicable
- Date ISRCTN created
- date ISRCTN requested
- Date Registered NTR7-sep-2017
- Secondary IDsMETC173030 METC azM/UM
- Public TitleEvaluation of boiled vs raw eggs for stimulating post-exercise muscle protein synthesis
- Scientific TitleEvaluation of boiled vs raw eggs for stimulating post-exercise muscle protein synthesis
- ACRONYM
- hypothesisWe hypothesize that the ingestion of boiled eggs will lead to significant higher rates of muscle protein synthesis compared to raw egg ingestion.
- Healt Condition(s) or Problem(s) studiedMuscle mass growth, Sarcopenia, Muscle protein synthesis
- Inclusion criteriaHealthy males
Age between 18 and 35 y inclusive
BMI between 18.5 and 30 kg/m2
- Exclusion criteriaAllergies to egg proteins
Smoking
Phenylketonuria
Diabetes Mellitus
Diagnosed GI tract disorders or diseases
Arthritic conditions
A history of neuromuscular problems
Any medications known to affect protein metabolism (i.e. corticosteroids, non-steroidal anti-inflammatories, or prescription strength acne medications).
Use of certain anticoagulants (use of thrombocyte 
aggregation inhibitors such as acetylsalicylic acid and carbasalaatcalcium is permitted. Use of
 other thrombocyte aggregation inhibitors will be discussed with the responsible physician)
Blood donation within 2 months of study initiation
Hypertension (according to WHO criteria)
- mec approval receivedyes
- multicenter trialno
- randomisedyes
- masking/blindingNone
- controlActive
- groupParallel
- Type2 or more arms, randomized
- Studytypeintervention
- planned startdate 1-dec-2017
- planned closingdate31-dec-2018
- Target number of participants30
- InterventionsEffect of raw or boiled eggs ingestion after exercise on muscle protein synthesis
- Primary outcomeMuscle protein synthesis
- Secondary outcomePlasma amino acid concentrations
- TimepointsMuscle biopsies will be taken at timepoints: 0, 2, 5 h after ingestion of the eggs
- Trial web site
- statusopen: patient inclusion
- CONTACT FOR PUBLIC QUERIES Cas Fuchs
- CONTACT for SCIENTIFIC QUERIES Cas Fuchs
- Sponsor/Initiator Maastricht University
- Funding
(Source(s) of Monetary or Material Support)
Maastricht University
- Publicationsn/a
- Brief summaryEggs are considered as a conventional “high-quality” dietary protein source as they contain all of the essential amino acids (EAA) and are highly digestible. Hence, the ingestion of eggs has been shown to stimulate skeletal muscle protein synthesis and is therefore considered as an optimal protein source to ingest after exercise. Eggs are generally boiled before consumption. However, they can also be ingested in other ways (e.g., raw). There is a lack of information in the way eggs might differ in their potential to stimulate skeletal muscle protein synthesis when ingested either boiled or raw. Therefore, the aim of the present study is to assess the capacity of egg protein either boiled or raw in stimulating post-exercise skeletal muscle protein synthesis and support protein anabolism in vivo in humans.
- Main changes (audit trail)
- RECORD7-sep-2017 - 7-okt-2017


  • Indien u gegevens wilt toevoegen of veranderen, kunt u een mail sturen naar nederlands@trialregister.nl