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Lexical Production and Cognitive Control in Bilinguals


- candidate number28390
- NTR NumberNTR6939
- ISRCTNISRCTN no longer applicable
- Date ISRCTN created
- date ISRCTN requested
- Date Registered NTR31-dec-2017
- Secondary IDsNL61816.058.17  METC LUMC
- Public TitleLexical Production and Cognitive Control in Bilinguals
- Scientific TitleLexical Production and Cognitive Control in Bilinguals
- ACRONYMLPCC in Bilinguals
- hypothesis- In bringing about an absence of standard language effect in bilinguals, the neural mechanisms which differentiate L1 and L2 lexical productions will no longer be different from each other and the same neural underpinnings will be involved in L1 and L2 lexical productions.
- In bringing about reversed language effect in bilinguals, cognitive control has a facilitatory function over L2 and an inhibitory function over L1. Such a function is also hypothesized to underlie lexical production in the intended language and the inhibition of such a production in the unintended language.
- Healt Condition(s) or Problem(s) studiedCognitive control, Bilingual, Lexical production
- Inclusion criteriaParticipants will be healthy, volunteer, right-handed Dutch-English bilinguals, without any report and history of neurological or psychiatric problems and no counter-indications to MRI. Their age will not be more than thirty. In addition, in this study upper intermediate bilinguals will be included and the main criteria to assess this level of bilingualism will be a quick placement test published by Oxford University Press.
- Exclusion criteriaLeft-handed volunteers, balanced bilinguals, bilinguals with less than upper intermediate proficiency in English language, the ones who are more than 30 years old, and have any report and history of neurological or psychiatric problems will be excluded from this study. Potential participants will be pre-screened for contraindications for fMRI, which include metal implants, heart arrhythmia, claustrophobia, and possible pregnancy (in females). They will additionally be pre-screened for head trauma, history of neurological or psychiatric illness and/or use of psychotropic medications. The ones with the positive results in pre-screen section will be excluded.
- mec approval receivedyes
- multicenter trialno
- randomisedno
- group[default]
- Type[default]
- Studytypeobservational
- planned startdate 3-jan-2018
- planned closingdate1-jul-2018
- Target number of participants50
- InterventionsNot applicable
- Primary outcomeThe main endpoints of the study are to delineate the way cognitive control contributes to absence of standard language effect and reversed language effect in bilinguals, when producing L1 and L2 lexical items.
- Secondary outcome- to define any differences in terms of the strength of functional connectivity in brain areas involved in cognitive control, between participants who show the reversed language effect more than the other group.
- to define how the perisylvian language network is different between participants who have a better performance in switching between first and second language lexical items than the ones with average performance in that regard.
- TimepointsThis experiment is expected to be completed in mid 2018.
- Trial web site
- statusplanned
- CONTACT FOR PUBLIC QUERIES Fatemeh Tabassi Mofrad
- CONTACT for SCIENTIFIC QUERIES Fatemeh Tabassi Mofrad
- Sponsor/Initiator Cognitive Psychology Unit of Leiden University
- Funding
(Source(s) of Monetary or Material Support)
Cognitive Psychology Unit of Leiden University
- PublicationsN/A
- Brief summaryThis research addresses the gap in the related state-of-the-art research, by investigating the way neural mechanisms function in bringing about reversed language effect, and absence of standard language effect in bilinguals, and the way cognitive control modulate such language behavior.
- Main changes (audit trail)
- RECORD31-dec-2017 - 18-jan-2018


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