search  
 


Home

Who are we?

Why
register?


Signup for
registration


Online registration

Log in to register
your trial


Search a trial

NRT en CCMO

Contact

NEDERLANDS





MetaRegister
van CCT (UK)


ISRCTN-Register
van CCT (UK)


Mediators and moderators of cognitive behavioral therapy for childhood anxiety disorders: information processing, emotion regulation and stressreactivity.


- candidate number2131
- NTR NumberNTR704
- ISRCTNISRCTN46352117
- Date ISRCTN created26-sep-2006
- date ISRCTN requested13-sep-2006
- Date Registered NTR14-jun-2006
- Secondary IDsN/A 
- Public TitleMediators and moderators of cognitive behavioral therapy for childhood anxiety disorders: information processing, emotion regulation and stressreactivity.
- Scientific TitleMediators and moderators of cognitive behavioral therapy for childhood anxiety disorders: information processing, emotion regulation and stressreactivity: a randomised controlled trial.
- ACRONYMN/A
- hypothesis1a. Changes in outcome measures of anxiety can be partly explained by changes in self-reported thougths; 1b. Changes in outcome measures of anxiety can be partly explained by changes in selective attention and by changes in fear relevant cognitive schema's; 2a. Changes in outcome measures of anxiety can be partly explained by changes in self-reported emotion regulation strategies; 2b. Changes in outcome measures of anxiety can be partly explained by changes in processes of attention regulation and by changes in underlying schema's of 'perceived control'; 3. Effortful control will moderate the treatment effect; 4. Executive functions will moderate the relation between mediators and the treatment effect. The treatment effect will be larger when executive functions are more developed; 5. Stress-reactivity will moderate the treatment effect; 6. Stress-reactivity is a vulnerability factor for developing an anxiety disorder and is an effect of an anxiety disorder; 7. Part of the variance in treatment effect can be explained by family characteristics (parents psychopathology and parenting style) and characteristics of the therapist.
- Healt Condition(s) or Problem(s) studiedAnxiety disorders
- Inclusion criteria1. DSM-IV anxiety disorder as primary diagnosis; 2. Age between 7-18 years; 3. IQ >= 80; 4. Informed consent from parents and child.
- Exclusion criteria1. Psychosis; 2. Obsessive compulsive disorder as primary disorder; 3. Posttraumatic stress disorder as primary disorder; 4. Acute stress disorder; 5. Drug and/or alcohol problems; 6. Selective mutism; 7. Current treatment with SSRI or treatment with SSRI within an half year before inclusion; 8. Psychotherapeutic treatment within the last half year.
- mec approval receivedyes
- multicenter trialyes
- randomisedyes
- masking/blindingNone
- controlNot applicable
- groupParallel
- Type-
- Studytypeintervention
- planned startdate 1-sep-2006
- planned closingdate1-sep-2008
- Target number of participants120
- InterventionsGroup 1: 12 sessions of Cognitive Behavioral Therapy according to the Coping Cat manual. 4 measure points: before therapy, after 8 sessions, after therapy and after 12 week follow-up period; Group 2: 8 week Waiting List group. Children will receive the same therapy as group 1 after the waiting period. There are 5 measure points: before waiting list, before therapy, after 8 sessions of therapy, after therapy and after 12 week follow-up period.
- Primary outcome1. Effect of treatment (diagnosis of anxiety disorder and scores on anxiety questionnaires); 2. Mediating effect of information processing; 3. Mediating effect of emotion regulation; 4. Moderating effect of effortful control, executive functions and stress-reactivity.
- Secondary outcome1. correlation between explicit and implicit measures; 2. development of implicit measures.
- Timepoints
- Trial web siteN/A
- statusopen: patient inclusion
- CONTACT FOR PUBLIC QUERIESProf. Dr. F. Boer
- CONTACT for SCIENTIFIC QUERIESProf. Dr. J.M. Prins
- Sponsor/Initiator Academic Medical Center (AMC), Amsterdam, University of Amsterdam (UvA), Department of Clinical Psychology , Accare, Division University Center for Child and Adolescent Psychiatry
- Funding
(Source(s) of Monetary or Material Support)
Academic Medical Center (AMC), Accare, University of Amsterdam (UvA), Department of Clinical Psychology
- PublicationsN/A
- Brief summaryAlthough cognitive behavioral therapy for childhood anxiety disorders has shown to be effective, little is known about the mechanisms that moderate or mediate the treatment effect. More knowledge about mediators and moderators can contribute to more specific and effective therapies. The objective of this study is to determine if cognitive restructuring and emotion regulation strategies are mechanisms of cognitive therapy for childhood anxiety disorders. Furthermore, the moderating effects of effortful control, executive functions and stress reactivity are studied.
- Main changes (audit trail)
- RECORD14-jun-2006 - 26-nov-2006


  • Indien u gegevens wilt toevoegen of veranderen, kunt u een mail sturen naar nederlands@trialregister.nl