search  
 


Home

Who are we?

Why
register?


Signup for
registration


Online registration

Log in to register
your trial


Search a trial

NRT en CCMO

Contact

NEDERLANDS





MetaRegister
van CCT (UK)


ISRCTN-Register
van CCT (UK)


Levetiracetam for Treatment of Non-psychotic and Non-depressive behavioural symptoms of dementia.


- candidate number2201
- NTR NumberNTR787
- ISRCTNISRCTN97133543
- Date ISRCTN created28-dec-2006
- date ISRCTN requested18-dec-2006
- Date Registered NTR8-aug-2006
- Secondary IDsN/A 
- Public TitleLevetiracetam for Treatment of Non-psychotic and Non-depressive behavioural symptoms of dementia.
- Scientific TitleLevetiracetam for Treatment of Non-psychotic and Non-depressive behavioural symptoms of dementia.
- ACRONYMLaTiNN
- hypothesisSpecific behavioural symptoms of dementia needs specific treatment. In cases, Levetiracetam seems to be effective in Non-psychotic and Non-depressive behavioural symptoms of dementia.
- Healt Condition(s) or Problem(s) studiedDementia
- Inclusion criteria1. Ambulant patients with dementia, level Reisberg 4-6;
2. Informant available.;
3. 6 weeks stable treatment of dementia; anti-psychotics and anti-depressants.
- Exclusion criteria1. NPI item hallucinations, delusions and depression > ;1
2. Epilepsia;
3. Alcoholism;
4. DM or thyroid disease not under control.
- mec approval receivedyes
- multicenter trialno
- randomisedno
- group[default]
- TypeSingle arm
- Studytypeintervention
- planned startdate 1-aug-2006
- planned closingdate1-apr-2007
- Target number of participants25
- Interventions500 mg Levetiracetam/day, maximum 1500 mg Levetiracetam/day.
- Primary outcomeEffect on week 4 and 13 compared to base-line on Behauvioral symptoms (NPI and CMAI), care-giver burden (CBI) and clinical impression (GCI).
- Secondary outcomeEffect on week 4 and 13 compared to base-line on cognition (MMSE) and ADL (IDDD).
- TimepointsN/A
- Trial web siteN/A
- statusinclusion stopped: follow-up
- CONTACT FOR PUBLIC QUERIESDr. P.L.J. Dautzenberg
- CONTACT for SCIENTIFIC QUERIESDr. P.L.J. Dautzenberg
- Sponsor/Initiator Jeroen Bosch Hospital, Department of Geriatrics
- Funding
(Source(s) of Monetary or Material Support)
UCB for support for statistical analysis if needed, however Dep geriatrics Utrecht University (Rob van Marum) will first performe this analysis
- PublicationsDautzenberg PLJ et al. Medicamenteuze behaneling van gedrags- en psychische problemen bij dementie (BPSD). Tijdschrift voor verpleeghuisgeneeskunde 2003;27(5):5-9. Weiner MF et al. Levetiracetam for agitated Alzheimer's disease patients. Int J Psychogeriatrics 2005;17(2):327-8.
- Brief summaryN/A
- Main changes (audit trail)
- RECORD8-aug-2006 - 24-nov-2009


  • Indien u gegevens wilt toevoegen of veranderen, kunt u een mail sturen naar nederlands@trialregister.nl