search  
 


Home

Who are we?

Why
register?


Signup for
registration


Online registration

Log in to register
your trial


Search a trial

NRT en CCMO

Contact

NEDERLANDS





MetaRegister
van CCT (UK)


ISRCTN-Register
van CCT (UK)


Reversibility of adrenal function in Addison's disease.


- candidate number2357
- NTR NumberNTR830
- ISRCTNIncomplete info for ISRCTN
- Date ISRCTN created
- date ISRCTN requested
- Date Registered NTR7-dec-2006
- Secondary IDs04-09-2007 METC UMC Utrecht
- Public TitleReversibility of adrenal function in Addison's disease.
- Scientific TitleReversibility of adrenal function in Addison's disease.
- ACRONYMN/A
- hypothesisThe aim of this study is to investigate reversibility of adrenal function in patients with autoimmune adrenalitis.
- Healt Condition(s) or Problem(s) studiedAddison's disease
- Inclusion criteria1. Patients with Addison's disease;
2. Age: 18-75 years;
3. Stable substitution therapy with glucocorticoids.
- Exclusion criteria1. Acute stress or illness;
2. Use of other medication containing glucocorticoids;
3. Allergy for synthetic ACTH;
4. Pregnancy;
5. Breast feeding.
- mec approval receivedyes
- multicenter trialno
- randomisedno
- group[default]
- Type2 or more arms, non-randomized
- Studytypeintervention
- planned startdate 22-dec-2006
- planned closingdate1-mrt-2007
- Target number of participants30
- InterventionsPerforming a Synacthen stimulation test.
- Primary outcomeCortisol concentration 30 and 60 minutes after Synacthen stimulation test.
- Secondary outcomeN/A
- TimepointsN/A
- Trial web siteN/A
- statusstopped: trial finished
- CONTACT FOR PUBLIC QUERIES L.C.C.J. Smans
- CONTACT for SCIENTIFIC QUERIES L.C.C.J. Smans
- Sponsor/Initiator University Medical Center Utrecht (UMCU), Department of Endocrinologie
- Funding
(Source(s) of Monetary or Material Support)
University Medical Center Utrecht (UMCU), Department of Endocrinologie
- PublicationsN/A
- Brief summaryAddison's disease is considered to be a chronic and incurable disease. Patients are treated with glucocorticoids and mineralocorticoids for life with possible side-effects of mild oversubstitution on the long term. It is possible that autoimmune mediated adrenalitis will not always lead to total or permanent destruction of all adrenocortical cells. This study will investigate (partial) reversibility of adrenal function in Addison's disease.
- Main changes (audit trail)
- RECORD7-dec-2006 - 20-okt-2009


  • Indien u gegevens wilt toevoegen of veranderen, kunt u een mail sturen naar nederlands@trialregister.nl