search  
 


Home

Who are we?

Why
register?


Signup for
registration


Online registration

Log in to register
your trial


Search a trial

NRT en CCMO

Contact

NEDERLANDS





MetaRegister
van CCT (UK)


ISRCTN-Register
van CCT (UK)


The pharmacokinetics of nimodipine, intravenous and orally, in patients with subarachnoidal hemorrhage admitted in the intensive care.


- candidate number2417
- NTR NumberNTR875
- ISRCTNISRCTN45381163
- Date ISRCTN created8-feb-2007
- date ISRCTN requested7-feb-2007
- Date Registered NTR19-jan-2007
- Secondary IDsN/A 
- Public TitleThe pharmacokinetics of nimodipine, intravenous and orally, in patients with subarachnoidal hemorrhage admitted in the intensive care.
- Scientific TitleThe pharmacokinetics of nimodipine, intravenous and orally, in patients with subarachnoidal hemorrhage admitted in the intensive care.
- ACRONYMNimodipine subarachnoidal hemorrhage ICU
- hypothesisDescribing the pharmacokinetics of nimodipine, especially the variability of bio-availability orally administred nimdipine.
- Healt Condition(s) or Problem(s) studiedSubarachnoid hemorrhage (SAH), Intensive care
- Inclusion criteria1. All patients admitted on the ICU with subarachnoidal hemorrhage (SAB), treated according to our SAB-protocol;
2. Adults aged 18 - 70 years old.
- Exclusion criteria1. Pregnancy;
2. Expected mortality < 24 hours;
3. Severe hepatic function disorders;
4. Use of medication with know interaction in relation to nimodipine.
- mec approval receivedyes
- multicenter trialno
- randomisedno
- group[default]
- TypeSingle arm
- Studytypeintervention
- planned startdate 1-dec-2006
- planned closingdate1-dec-2007
- Target number of participants12
- InterventionsBloodsamples according to strict time protocol during treatment.
- Primary outcome1. Pharmacokinetics of nimodipine in this specific group of patients;
2. Variability of bio-availability of orally administred nimodipine.
- Secondary outcomeN/A
- TimepointsN/A
- Trial web siteN/A
- statusinclusion stopped: follow-up
- CONTACT FOR PUBLIC QUERIESfellow intensive care B.M. Kors
- CONTACT for SCIENTIFIC QUERIESProf. dr. A.R.J Girbes
- Sponsor/Initiator VU University Medical Center, Department of Intensive Care
- Funding
(Source(s) of Monetary or Material Support)
VU University Medical Center, Department of Intensive Care
- PublicationsN/A
- Brief summaryThe pharmacokinetics of nimodipine, intravenous and orally, in patients with subarachnoidal hemorrhage admitted in the intensive care. Use of nimodipine in this specific group of patients according to our SAB protocol. Measurement of nimodipine blood levels during intravenous and orally administration.
- Main changes (audit trail)
- RECORD19-jan-2007 - 18-jan-2010


  • Indien u gegevens wilt toevoegen of veranderen, kunt u een mail sturen naar nederlands@trialregister.nl